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Retroviral-like features in the monomer of the major satellite DNA from the South American rodents of the genus Ctenomys.
Rossi, M S; Pesce, C G; Reig, O A; Kornblihtt, A R; Zorzópulos, J.
Afiliação
  • Rossi MS; GIBE, Department of Biology, FCEyN, University of Buenos Aires, Argentina.
DNA Seq ; 3(6): 379-81, 1993.
Article em En | MEDLINE | ID: mdl-8219281
It is well known that uninfected mammalian cells contain DNA sequences which are closely related to retroviral genomic segments. However, these sequences seldom (if ever) have been found associated to highly repetitive (satellite) DNA. RPCS is a 348 bp monomer of a major satellite DNA from the South American rodents of the genus Ctenomys. It was found that RPCS contains several elements which are typical of the U3 region of retroviral LTRs. These elements are: a) a polypurine tract; b) two enhancer core sequences; c) two NF1 binding sites; d) two C/EBP binding sites; e) two CCAAT-motifs; f) a TATA box, and g) two putative polyadenylation motifs. Furthermore, the relative positions of these elements are as in the U3 retroviral regions.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retroviridae / Roedores / DNA Satélite Limite: Animals Idioma: En Revista: DNA Seq Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 1993 Tipo de documento: Article País de afiliação: Argentina País de publicação: Reino Unido
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retroviridae / Roedores / DNA Satélite Limite: Animals Idioma: En Revista: DNA Seq Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 1993 Tipo de documento: Article País de afiliação: Argentina País de publicação: Reino Unido