Natural and induced blood dissemination of Toxoplasma gondii: experimental model in white mice and hamsters.
Rev Biol Trop
; 41(2): 197-202, 1993 Aug.
Article
em En
| MEDLINE
| ID: mdl-8184150
Blood inoculation in mice showed that Toxoplasma organisms circulate in blood after 1 h of oocyst infection. Parasites were detected up to 15 days later and then disappeared from the bloodstream concomitantly with cyst formation in the brain, probably due to antibody presence. Immunosuppression caused by cortisone acetate treatment induced Toxoplasma bloodstream invasion in chronically infected mice and hamsters, causing death in some. Natural dissemination is discussed in relation with congenital toxoplasmosis. Induced immunosuppressive effect is compared with that produced by natural diseases such as Hodgkin, lymphoma, AIDS and others.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Toxoplasma
/
Toxoplasmose Animal
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Rev Biol Trop
Ano de publicação:
1993
Tipo de documento:
Article
País de publicação:
Costa Rica