[Effects of 1,5 benzodiazepine beta lactam on sleep]. / Efecto de una beta lactama de 1.5 benzodiazepina sobre el sueño.
Gac Med Mex
; 129(2): 119-23, 1993.
Article
em Es
| MEDLINE
| ID: mdl-7926392
Various substances have been used as sleep inductors, but their use has declined, due to their undesirable side effects, and they have been replaced mainly by benzodiazepines. There currently exists a great variety of benzodiazepines with an increasing, clinical use, although they also present certain disadvantages. The effect on sleep of the intraperitoneal administration (0.9 mg/kg) of 7-(p-cl-phenyl)-8-phenoxy-4,5-benzo-3-aza-2-none, was analysed in chronically implanted wistar rats. Results indicate that this substance decreases wakefulness and increases significantly slow-wave and paradoxical sleep. Latency of the first phase of paradoxical sleep show a tendency to increase. It is concluded that this substance has hypnogenic effects.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sono
/
Ansiolíticos
Limite:
Animals
Idioma:
Es
Revista:
Gac Med Mex
Ano de publicação:
1993
Tipo de documento:
Article
País de publicação:
México