Cardiac and neurologic complications in malignant hypertension due to oral contraceptive use.
Blood Press
; 3(5): 319-21, 1994 Sep.
Article
em En
| MEDLINE
| ID: mdl-7866596
ABSTRACT
PIP: Although an association between oral contraceptives (OCs) and arterial hypertension has been well-documented, most studies have found only mild or moderate hypertension with reversal to normal levels 3 months after OC discontinuation. This paper presents two cases in which young women developed severe left ventricular hypertrophy and renal failure due to OC-induced malignization of hypertension. The first patient, a 23-year-old, was admitted to the hospital with a 3-day history of headache, mental confusion, and aggressiveness. 6 months before presentation, severe arterial hypertension had been diagnosed. At that time, she was advised to discontinue OCs (30 mcg of ethinyl estradiol and 150 mcg of levonorgestrel), which she had been taking for a year; she did not comply with this directive. The second patient, 21 years old, was admitted with accelerating hypertension. She had initiated OC use (30 mg of ethinyl estradiol and 150 mcg of levonorgestrel) 6 months earlier. 3 months after starting OC use, she developed headache and fatigue. Both women had a hemorrhagic cerebral accident as a complication of malignant hypertension. All neurologic, renal, and cardiovascular complications were reversible after OC discontinuation. OC-related malignant hypertension can be averted through effective control of blood pressure in OC users.
Palavras-chave
Biology; Blood Pressure; Case Studies; Cerebrovascular Effects; Contraception; Contraceptive Methods--side effects; Diseases; Family Planning; Hemic System; Hypertension; Neurologic Effects; Oral Contraceptives--side effects; Physiology; Renal Effects; Research Methodology; Research Report; Studies; Urogenital Effects; Urogenital System; Vascular Diseases
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemorragia Cerebral
/
Levanogestrel
/
Hipertrofia Ventricular Esquerda
/
Etinilestradiol
/
Injúria Renal Aguda
/
Hipertensão Maligna
Tipo de estudo:
Etiology_studies
/
Guideline
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Blood Press
Assunto da revista:
ANGIOLOGIA
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Reino Unido