Dosage compensation in sciarids is achieved by hypertranscription of the single X chromosome in males.
Genetics
; 138(3): 787-90, 1994 Nov.
Article
em En
| MEDLINE
| ID: mdl-7851774
Dosage compensation refers to the process whereby females and males with different doses of sex chromosomes have similar amounts of products from sex chromosome-linked genes. We analyzed the process of dosage compensation in Sciara ocellaris, Diptera of the suborder Nematocera. By autoradiography and measurements of X-linked rRNA in females (XX) and males (XO), we found that the rate of transcription of the single X chromosome in males is similar to that of the two X chromosomes in females. This, together with the bloated appearance of the X chromosome in males, support the idea that in sciarids dosage compensation is accomplished by hypertranscription of the X chromosome in males.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transcrição Gênica
/
Cromossomo X
/
Mecanismo Genético de Compensação de Dose
/
Dípteros
Limite:
Animals
Idioma:
En
Revista:
Genetics
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Estados Unidos