Nuclear presence of two lysosomal enzymes in rat implantation sites.
Int J Fertil Menopausal Stud
; 39(5): 299-303, 1994.
Article
em En
| MEDLINE
| ID: mdl-7820164
OBJECTIVE: To test the Szego hypothesis of increased beta-glucuronidase and acid phosphatase activities in hormone target tissues. METHODS: The presence of beta-glucuronidase and acid phosphatase activities in nuclear subcellular fractions obtained from decidual (implantation site) and stromal (nonimplantation zone) tissues was demonstrated by both biochemical measurements and ultramicrographic analysis utilizing a histochemical reaction. RESULTS: Acid phosphatase was almost twice as abundant in nuclei and lysosomes of epithelial cells (implantation sites), and beta-glucuronidase also was significantly more active in nuclei from epithelial and decidual tissues than in nonimplantation tissue. CONCLUSION: Our results, utilizing the implantation process as experimental model, support the Szego hypothesis of the lysosomal role in hormonal mechanisms of action.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Implantação do Embrião
/
Fosfatase Ácida
/
Núcleo Celular
/
Glucuronidase
/
Lisossomos
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Int J Fertil Menopausal Stud
Assunto da revista:
GINECOLOGIA
/
MEDICINA REPRODUTIVA
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
México
País de publicação:
Estados Unidos