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[Immune response to poliovirus]. / Respuesta inmune a poliovirus.
Díaz-Ortega, J L; Pontes-González, E; Solano-Mejía, B V; Zárate-Aquino, M L; Camacho-Amor, M L; Chávez-San Juan, R.
Afiliação
  • Díaz-Ortega JL; Instituto Nacional de Diagnóstico y Referencia Epidemiológicos, México, D.F.
Bol Med Hosp Infant Mex ; 50(5): 347-58, 1993 May.
Article em Es | MEDLINE | ID: mdl-7684921
General aspects on the immune response to poliovirus are described, considering it's molecular structure. Since the poliovirus is a cytocide agent, antibody immune response is the most important among those related to protection; however probably a minimum of helper T cells are required (more than 200 T lymphocytes with phenotype CD4) in order to get a best response. Phagocyte, NK cells and T lymphocytes probably take part in the viral clearance from the central nervous system, also in the host injure mechanisms. Some molecular aspects of the neutralizing antibodies combining site are described too. Activation particularities, of the common mucosal immune system confirm the importance of the secretory immune response in the control of the poliomyelitis.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poliomielite / Poliovirus Limite: Child / Humans Idioma: Es Revista: Bol Med Hosp Infant Mex Ano de publicação: 1993 Tipo de documento: Article País de publicação: México
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poliomielite / Poliovirus Limite: Child / Humans Idioma: Es Revista: Bol Med Hosp Infant Mex Ano de publicação: 1993 Tipo de documento: Article País de publicação: México