Prevalence of human papillomavirus among STD clinic attenders in Jamaica: association of younger age and increased sexual activity.
Sex Transm Dis
; 22(2): 114-8, 1995.
Article
em En
| MEDLINE
| ID: mdl-7624812
ABSTRACT
PIP: During November 1990-January 1991, DNA was extracted from cervicovaginal cells from 202 women attending the Comprehensive Health Centre, a sexually transmitted disease (STD) clinic, in Kingston, Jamaica, to determine the prevalence of human papilloma virus (HPV). Health workers interviewed these women so researchers could identify risk factors for HPV. 58 women (28.7%) tested positive for HPV. 62% had uncharacterized HPV DNA types. 16% had more than one type of HPV. HPV prevalence fell with age (39% for 15-19 year olds, 33% for 20-24 year olds, 31% for 25-29 year olds and 17% for 30+ year olds; odds ratio [OR] for oldest group = 0.34; p = 0.025), suggesting that older women have developed an immunity to HPV infection. The higher the number of years of sexual activity, the lower the HPV prevalence (40% for 1-4 years, 32% for 5-9 years, and 23% for 10+ years; OR for 10+ years was 0.44; p = 0.03). Women with at least two sexual partners over the last 12 months had a higher HPV prevalence than those with fewer sexual partners (OR = 2.87; p = 0.01). The greater the average number of times women claimed to have had vaginal intercourse per month in the last year, the greater the HPV prevalence (OR for 3-4 times = 2.07, OR for 5+ times = 3.22; p = 0.006). A multiple logistic regression analysis revealed that age confounded the inverse association between HPV prevalence and years of sexual activity. 3% of Pap smears exhibited cervical dysplasia. Further studies are needed to obtain a better understanding of why immunity to HPV may occur in older women. This information could form the basis for developing an effective vaccine against cervical cancer.
Palavras-chave
Age Factors; Americas; Behavior; Cancer; Caribbean; Cervical Cancer--prevention and control; Coital Frequency; Demographic Factors; Developing Countries; Diseases; Health; Health Surveys; Hpv; Infections; Jamaica; Measurement; Multiple Partners; Neoplasms; North America; Population; Population Characteristics; Prevalence; Reproductive Tract Infections; Research Report; Sex Behavior; Sexual Partners; Sexually Transmitted Diseases; Viral Diseases
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Tumorais por Vírus
/
Doenças Virais Sexualmente Transmissíveis
/
Infecções por Papillomavirus
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
País/Região como assunto:
Caribe ingles
/
Jamaica
Idioma:
En
Revista:
Sex Transm Dis
Ano de publicação:
1995
Tipo de documento:
Article
País de publicação:
Estados Unidos