The heterogeneity of the beta s cluster haplotypes in Brazil.
Gene Geogr
; 8(1): 7-12, 1994 Apr.
Article
em En
| MEDLINE
| ID: mdl-7619778
The beta s cluster haplotypes were determined for 74 Brazilian patients with sickle cell anemia from three cities separated by 1,400 to 2,300 km. The cities are representative of the regions which have the largest Black populations of the country. All 138 chromosomes with typical haplotypes had one of the three most common African haplotypes. No example of the Asian or of the Cameroon haplotypes was found. The Bantu haplotype predominates in all three regions (54.8 to 73.1%), followed by the Benin haplotype (25.4 to 45.2%) and a small number of cases with the Senegal haplotype (0 to 6.9%). The mean prevalence of the Bantu haplotype of 65.9% agrees closely with historical data which indicate that 70% of the African slaves brought to Brazil originated from regions of Bantu populations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemoglobina Falciforme
/
Heterogeneidade Genética
/
Anemia Falciforme
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Africa
/
America do sul
/
Brasil
Idioma:
En
Revista:
Gene Geogr
Assunto da revista:
GENETICA MEDICA
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Itália