Hyperglycemia associated with the therapeutic use of L-asparaginase: possible role of insulin receptors.
J Pediatr
; 93(5): 775-8, 1978 Nov.
Article
em En
| MEDLINE
| ID: mdl-712479
A study of four children, two with acute lymphocytic leukemia and two with non-Hodgkin lymphoma, treated for three days with L-asparaginase, suggests that insulin receptors may be involved in the hyperglycemia associated with the use of L-asparaginase. Comparison of insulin receptors of circulating monocytes revealed a marked decrease in their number after treatment. This might also explain the lack of response to insulin treatment in one of the patients with symptomatic hyperglycemia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asparaginase
/
Receptor de Insulina
/
Hiperglicemia
Tipo de estudo:
Risk_factors_studies
Limite:
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Pediatr
Ano de publicação:
1978
Tipo de documento:
Article
País de publicação:
Estados Unidos