Conversion of the C3 component of complement in sera of hanseniasis patients.

Kliemann, T A; Martinez, E L; Irulegui, I; de Souza, Z W; Cavalcanti, Z M

Kliemann, T A; Martinez, E L; Irulegui, I; de Souza, Z W; Cavalcanti, Z M.

Hansenol Int ; 8(1): 5-8, 1983 Jun.

Article em En | MEDLINE | ID: mdl-6432691

RESUMO

The levels of total C3 (native C3 plus its degradation products) and the degree of conversion of native C3 into its breakdown products were studied in sera of Virchowian (V), tuberculoid (T), indeterminate (I), and Virchowian with erythema nodosum Hansenicum (ENH) patients. Sera from normal individuals (N) were also analysed. While the levels of total C3 were not significantly different among the groups, the percentage of conversion of C3 into its degradation products was significantly higher in V and ENH sera. The activation of the complement system and the involvement of immune complexes (IC) are discussed.

Assuntos

Complexo Antígeno-Anticorpo/imunologia; Ativação do Complemento; Complemento C3/metabolismo; Hanseníase/imunologia; Humanos; Imunodifusão; Imunoeletroforese

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complemento C3 / Ativação do Complemento / Hanseníase / Complexo Antígeno-Anticorpo Limite: Humans Idioma: En Revista: Hansenol Int Ano de publicação: 1983 Tipo de documento: Article País de publicação: Brasil

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