Changes in plasma aldosterone levels and renin activity after bilateral superior cervical ganglionectomy in two strains of rats.
Acta Physiol Pharmacol Latinoam
; 34(3): 263-9, 1984.
Article
em En
| MEDLINE
| ID: mdl-6241783
Superior cervical ganglionectomy (SCGx) of Wistar rats brought about a significant increase of plasma renin activity (PRA) 9 or 15 days later, an effect not observed 48 days after surgery. The same surgical procedure performed in Chbb Tom rats did not result in significant modification of PRA. In both strains of rats immobilization stress induced a 2.3-3.3-fold increase of PRA regardless of whether the animals had intact superior cervical ganglia. The injection of the angiotensin-converting enzyme inhibitor captopril to SCGx Wistar rats at the time of elevated PRA induced a severe hypotension, while it did not affect blood pressure in sham-operated animals. In both strains of rats SCGx resulted in depressed circulating aldosterone levels at all studied times after surgery.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Simpatectomia
/
Renina
/
Aldosterona
Limite:
Animals
Idioma:
En
Revista:
Acta Physiol Pharmacol Latinoam
Assunto da revista:
FARMACOLOGIA
/
FISIOLOGIA
Ano de publicação:
1984
Tipo de documento:
Article
País de publicação:
Argentina