Neurological disease in man following administration of suckling mouse brain antirabies vaccine.
Bull World Health Organ
; 46(3): 321-7, 1972.
Article
em En
| MEDLINE
| ID: mdl-4339746
In Latin America, suckling mouse brain (SMB) vaccine has become the most commonly used vaccine for immunization of both man and animals against rabies. This vaccine is highly immunogenic, is relatively economical and easy to produce, and is believed to be free of the immunoencephalitogenic factor. From 1964 to the end of 1969, there were 40 reported cases of neurological disease following administration of SMB vaccine, 32 of which met the criteria for inclusion in this report. These 32 cases occurred in 8 different countries. In contrast to neurological disease following the administration of other types of nervous tissue vaccine, the majority of the cases following vaccination with SMB vaccine had a Guillain-Barré-type syndrome with peripheral nervous system involvement and a higher case-fatality rate. The causative agent has not been demonstrated. Modifications in the production and handling of the vaccine may be producing changes that are responsible.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polirradiculopatia
/
Vacina Antirrábica
/
Doenças do Sistema Nervoso Central
/
Doenças do Sistema Nervoso Periférico
Limite:
Animals
/
Humans
País/Região como assunto:
America do sul
Idioma:
En
Revista:
Bull World Health Organ
Ano de publicação:
1972
Tipo de documento:
Article
País de publicação:
Suíça