Gastroesophageal reflux causing respiratory distress and apnea in newborn infants.
J Pediatr
; 95(5 Pt 1): 763-8, 1979 Nov.
Article
em En
| MEDLINE
| ID: mdl-39984
Respiratory distress, apnea, and chronic pulmonary disease since birth were identified in 14 infants who also had symptomatic gastroesophageal reflux. Birth weights varied from 760 to 4,540 gm. All infants had radiographic changes similar to those in bronchopulmonary dysplasia. Cessation of apnea and improvement of pulmonary disease occurred only after medical (8) or surgical (6) control of gastroesophageal reflux. Simultaneous tracings of esophageal pH, heart rate, impedance pneumography, and nasal air flow in five infants demonstrated that reflux preceded apnea. Apnea could be induced by instillation of dilute acid, but not water or formula, into the esophagus. Prolonged monitoring of esophageal pH more than two hours after feeding in 14 other infants less than 6 weeks of age (birth weight 780 to 3,350 gm) without a history of recent vomiting indicated that reflux was not greater than in normal older children.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apneia
/
Síndrome do Desconforto Respiratório do Recém-Nascido
/
Refluxo Gastroesofágico
/
Doenças do Recém-Nascido
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
J Pediatr
Ano de publicação:
1979
Tipo de documento:
Article
País de publicação:
Estados Unidos