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Shorter Telomere Length is Associated with Food Insecurity in Older People: A Cross-Sectional Study.
Polo, Celi Macedo; Pereira de Brito, Tábatta Renata; Roberto Silva, Wanderson; Lima, Daniela Braga; Nunes, Daniella Pires; Colombo, Fábio Antonio; Orlandi, Ariene Angelini Dos Santos; Corona, Ligiana Pires.
Afiliação
  • Polo CM; Nutrition School, Federal University of Alfenas, Alfenas, Brazil.
  • Pereira de Brito TR; Nutrition School, Federal University of Alfenas, Alfenas, Brazil.
  • Roberto Silva W; Postgraduate Program in Food, Nutrition and Food Engineering, Sao Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
  • Lima DB; Nutrition School, Federal University of Alfenas, Alfenas, Brazil.
  • Nunes DP; Nursing school, University of Campinas, Campinas, Brazil.
  • Colombo FA; Pharmaceutical Sciences School, Federal University of Alfenas, Alfenas, Brazil.
  • Orlandi AADS; Nursing Department, Federal University of São Carlos, São Carlos, Brazil.
  • Corona LP; Applied Sciences School, University of Campinas, Campinas, Brazil.
Curr Aging Sci ; 2024 Oct 09.
Article em En | MEDLINE | ID: mdl-39410901
ABSTRACT

BACKGROUND:

Telomere length has been investigated as a biomarker of biological aging and is associated with several diseases, lifestyle, and socioeconomic factors.

OBJECTIVE:

This study aimed to verify whether food insecurity is associated with shorter telomere length in older people.

METHODS:

This is a cross-sectional study carried out in a municipality in the interior of Brazil, with a sample of 440 older people from the community. For telomere length analysis, a blood sample was obtained from each participant, followed by real-time qPCR, and sociodemographic and health information was collected through interviews. Food security/insecurity was measured using the reduced version of the Brazilian Food Insecurity Scale. Descriptive analysis and multiple logistic regression were performed to analyze the factors associated with shorter telomere length, adopting a significance level of 5%.

RESULTS:

We found that food insecurity was significantly associated with shorter telomere length, regardless of age group, skin color, tabagism, physical activity, milk and dairy consumption, living arrangement, and basic activities of daily life.

CONCLUSION:

The findings show the importance of ensuring full access to adequate nutrition for the older population, who are physiologically and socially vulnerable.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Curr Aging Sci Assunto da revista: GERIATRIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Curr Aging Sci Assunto da revista: GERIATRIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos