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Effect of Photobiomodulation on an Experimental Model of Lower Limb Ischemia.
Perez, Silvana Torres; Andreo, Lucas; Junior, José Antonio Silva; Bussadori, Sandra Kalil; Horliana, Anna Carolina Ratto Tempestini; Mesquita-Ferrari, Raquel Agnelli; Fernandes, Kristianne Porta Santos.
Afiliação
  • Perez ST; Postgraduate Program in Biophotonics Medicine, Nove de Julho University/UNINOVE, São Paulo, Brazil.
  • Andreo L; Conjunto Hospitalar Do Mandaqui, São Paulo, Brazil.
  • Junior JAS; Postgraduate Program in Biophotonics Medicine, Nove de Julho University/UNINOVE, São Paulo, Brazil.
  • Bussadori SK; Postgraduate Program in Biophotonics Medicine, Nove de Julho University/UNINOVE, São Paulo, Brazil.
  • Horliana ACRT; Postgraduate Program in Medicine, Nove de Julho University/UNINOVE, São Paulo, Brazil.
  • Mesquita-Ferrari RA; Postgraduate Program in Biophotonics Medicine, Nove de Julho University/UNINOVE, São Paulo, Brazil.
  • Fernandes KPS; Postgraduate Program in Rehabilitation Sciences, Nove de Julho University/UNINOVE, São Paulo, Brazil.
J Biophotonics ; : e202400305, 2024 Oct 14.
Article em En | MEDLINE | ID: mdl-39401766
ABSTRACT
Photobiomodulation (PBM) has been shown to be promising for the promotion of angiogenesis. The present study investigated the effects of PBM on vascularization in an animal model of peripheral artery disease. Wistar rats were divided into three groups. The control group received no procedures. The ischemia group was submitted to ligation of the femoral artery of the hindleg. The ischemia + PBM group was submitted to ligation of the femoral artery followed by PBM (660 and 808 nm, 100 mW, 4 J) over the site. Animals with ischemia treated with PBM exhibited comparable results to the control group with regards to the diameter of the α-SMA+ vessels, cross-sectional area of muscle fibers, percentage of collagen and serum concentration of IL-17A, as well as similarities in terms of vertical mobility, temperature of the hindleg, number of acts of grooming, and percentage of movement, indicating a condition like that of limbs unaffected by ischemia.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Biophotonics Assunto da revista: BIOFISICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Biophotonics Assunto da revista: BIOFISICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha