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Deciphering Osteosarcopenia through the hallmarks of aging.
Franulic, Francisca; Salech, Felipe; Rivas, Daniel; Duque, Gustavo.
Afiliação
  • Franulic F; Sección de Geriatría, Hospital Clínico Universidad de Chile, Santiago de Chile, Chile; Centro de Investigación Clínica Avanzada (CICA), Hospital Clínico Universidad de Chile, Santiago de Chile, Chile.
  • Salech F; Sección de Geriatría, Hospital Clínico Universidad de Chile, Santiago de Chile, Chile; Centro de Investigación Clínica Avanzada (CICA), Hospital Clínico Universidad de Chile, Santiago de Chile, Chile; Ageing and Quality of life Nucleus, INTA, Universidad de Chile, Santiago de Chile, Chile; Centre FO
  • Rivas D; Bone, Muscle & Geroscience Group, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
  • Duque G; Bone, Muscle & Geroscience Group, Research Institute of the McGill University Health Centre, Montreal, QC, Canada; Dr Joseph Kaufmann Chair in Geriatric Medicine, Department of Medicine, McGill University, Montreal, QC, Canada. Electronic address: gustavo.duque@mcgill.ca.
Mech Ageing Dev ; 222: 111997, 2024 Oct 11.
Article em En | MEDLINE | ID: mdl-39396681
ABSTRACT
Osteosarcopenia is a major driver of functional loss and a risk factor for falls, fractures, disability and mortality in older adults, urgently requiring the development of effective interventions to address it. The hallmarks of aging provide a theoretical and practical framework that allows for the structured organization of current knowledge and the planning of new development lines. This article comprehensively reviews the currently available literature on the role of the hallmarks of aging in the development of osteosarcopenia, thereby offering a panoramic view of the state of the art and knowledge gaps in this field.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mech Ageing Dev Ano de publicação: 2024 Tipo de documento: Article País de publicação: Irlanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mech Ageing Dev Ano de publicação: 2024 Tipo de documento: Article País de publicação: Irlanda