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Comparison of patch testing Brazilian (Green) propolis and Chinese (poplar-type) propolis: Clinical epidemiological study using data from the Information Network of Departments of Dermatology (IVDK).
Piontek, K; Radonjic-Hoesli, S; Grabbe, J; Drewitz, K P; Apfelbacher, C; Wöhrl, S; Simon, D; Lang, C; Schubert, S.
Afiliação
  • Piontek K; Information Network of Departments of Dermatology (IVDK), Institute at the University Medical Center Göttingen, Göttingen, Germany.
  • Radonjic-Hoesli S; Institute for Social Medicine and Health Systems Research, Medical Faculty Magdeburg, Magdeburg, Germany.
  • Grabbe J; Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Drewitz KP; Department of Dermatology, Cantonal Hospital Aarau, Aarau, Switzerland.
  • Apfelbacher C; Information Network of Departments of Dermatology (IVDK), Institute at the University Medical Center Göttingen, Göttingen, Germany.
  • Wöhrl S; Institute for Social Medicine and Health Systems Research, Medical Faculty Magdeburg, Magdeburg, Germany.
  • Simon D; Information Network of Departments of Dermatology (IVDK), Institute at the University Medical Center Göttingen, Göttingen, Germany.
  • Lang C; Institute for Social Medicine and Health Systems Research, Medical Faculty Magdeburg, Magdeburg, Germany.
  • Schubert S; Floridsdorf Allergy Center, Vienna, Austria.
Contact Dermatitis ; 2024 Oct 05.
Article em En | MEDLINE | ID: mdl-39367763
ABSTRACT

BACKGROUND:

Propolis types differ regarding their chemical composition.

OBJECTIVES:

To compare patch test results based on Brazilian (Green) propolis with data based on Chinese (poplar-type) propolis, and to evaluate the specifications of raw materials used for the PT preparations.

METHODS:

In the Information Network of Departments of Dermatology (IVDK), 1290 consecutive patients were patch tested with Brazilian (Green) propolis (NH400, SmartPractice Europe). Patch test reactivity was compared with results obtained with Chinese (poplar-type) propolis (NA71, SmartPractice Europe) by calculating frequencies and corresponding 95% confidence intervals. Data on the specifications of raw materials used for NH400 and NA71 were obtained from the manufacturer.

RESULTS:

Positive reactions to NH400 were found in 303 (23.5%) patients with unclear clinical relevance in most cases. Patients reacting to NH400 were less often sensitised to fragrances and colophony, but more often to nickel sulphate and cobalt chloride than patients reacting to NA71. The NH400 batch used contained high levels of aerobic bacteria, and was not purified by ethanolic extraction.

CONCLUSIONS:

Pattern of concomitant reactivity along with raw material properties suggests that the high frequency of positive reactions to NH400 may primarily result from bacterial contamination or impurities in the PT preparation rather than from propolis constituents.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Brasil Idioma: En Revista: Contact Dermatitis Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Brasil Idioma: En Revista: Contact Dermatitis Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido