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The short-term outcomes and risk factors of post-myocardial infarction ventricular septal rupture: a multi-center retrospective Study.
Luo, Wenjian; Wen, Li; Zhang, Jinning; Zhao, Junyong; Wang, Zelan; Luo, Xiaolin; Pi, Shixian; Chen, Yang; Zhang, Jiawen; Li, Tao; Zhang, Zhihui; Luo, Dan; Qin, Zhexue; Yu, Shiyong.
Afiliação
  • Luo W; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
  • Wen L; Department of Cardiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zhang J; Quality Control Section, the First Affiliated Hospital, Army Medical University, Chongqing, 400038, China.
  • Zhao J; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
  • Wang Z; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
  • Luo X; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
  • Pi S; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
  • Chen Y; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
  • Zhang J; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
  • Li T; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
  • Zhang Z; Department of Cardiology, the First Affiliated Hospital, Army Medical University, Chongqing, China.
  • Luo D; Quality Control Section, the First Affiliated Hospital, Army Medical University, Chongqing, 400038, China. 69589180@qq.com.
  • Qin Z; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China. zhexueqin@126.com.
  • Yu S; Department of Cardiology, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China. doctoryushiyong@163.com.
J Cardiothorac Surg ; 19(1): 571, 2024 Oct 01.
Article em En | MEDLINE | ID: mdl-39354610
ABSTRACT

OBJECTIVES:

Post-myocardial infarction ventricular septal rupture (PIVSR) is one of the most severe types of mechanical complications after acute myocardial infarction (AMI) with high mortality and poor prognosis. The risk factors for short-term mortality of patients with PIVSR may be not widely recognized. We aimed to assess the prevalence and short-term mortality risk predictors of PIVSR.

METHODS:

A total of 62 patients with a diagnosis of PIVSR were admitted to three top general public hospitals in Chongqing, China. Clinical characteristics and short-term outcomes of patients with PIVSR were compared. Predictors of PIVSR were assessed using logistic regression analysis.

RESULTS:

Mean age was 70.7 ± 10.7 years (38.7% female). The overall in-hospital mortality of PIVSR remained high (71%). Most (47/62) of the patients were in Killip class III or IV at the time of rupture diagnosis. Logistic regression analysis revealed that white blood cell count (WBC, OR 1.619, 95% CI 1.172-2.237, P = 0.005), cardiogenic shock (OR 47.706, 95%CI 2.859-795.945, P = 0.007) and left ventricular ejection fraction (LVEF, OR 0.803, 95%CI 0.689-0.936, P = 0.009) were independent risk factors of in-hospital early mortality. The nomogram developed for predicting the risk of short-term mortality showed a robust discrimination, with an area under the receiver operating characteristic curve (AUC) of 0.956 (95%CI 0.912-1.000).

CONCLUSION:

The short-term mortality of PIVSR remained high. WBC, cardiogenic shock, and LVEF were the independent predictive factors of short-term mortality. Our nomogram might be used to predict early mortality of patients with PIVSR.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mortalidade Hospitalar / Ruptura do Septo Ventricular / Infarto do Miocárdio Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: J Cardiothorac Surg Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mortalidade Hospitalar / Ruptura do Septo Ventricular / Infarto do Miocárdio Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: J Cardiothorac Surg Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido