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Antibiotic prescribing patterns in pediatric patients using the WHO access, watch, reserve (AWaRe) classification at a quaternary hospital in Nampula, Mozambique.
Xavier, Sancho Pedro; da Silva, Ageo Mario Cândido; Victor, Audêncio.
Afiliação
  • Xavier SP; Institute of Collective Health, Federal University of Mato Grosso, Av. Fernando Correa da Costa, 2367 - Bairro Boa Esperança, Cuiabá, Mato Grosso, 78060-900, Brazil. sanchoxavierxavier@gmail.com.
  • da Silva AMC; Institute of Collective Health, Federal University of Mato Grosso, Av. Fernando Correa da Costa, 2367 - Bairro Boa Esperança, Cuiabá, Mato Grosso, 78060-900, Brazil.
  • Victor A; School of Public Health, University of São Paulo (USP), Avenida Doutor Arnaldo, 715, São Paulo, 01246904, Brazil.
Sci Rep ; 14(1): 22719, 2024 09 30.
Article em En | MEDLINE | ID: mdl-39349590
ABSTRACT
Antibiotics are often prescribed inappropriately, either when they are not needed or with an unnecessarily broad spectrum of activity. This is a serious problem that can lead to the development of antimicrobial resistance (AMR). This study was conducted to assess the antibiotic prescribing pattern in pediatric patients hospitalized at a quaternary hospital in Nampula, Mozambique, using the WHO indicators and Framework as a reference. A retrospective study was conducted using secondary data obtained from medical records. The study population consisted of children aged 0-10 years who were hospitalized in a quaternary-level hospital ward in Nampula, Mozambique. The pattern of antibiotic prescriptions was assessed using indicators and the WHO classification of antibiotics into AWaRe categories. Descriptive statistics were applied. A total of 464 antibiotics were prescribed during the study. The age groups of 1-3 years and 28 days-12 months were prescribed more antibiotics. The most common antibiotics were ceftriaxone and crystallized penicillin, which were frequently prescribed for patients suffering from bronchopneumonia, gastroenteritis, and malaria. 74.8% of the antibiotics prescribed belonged to the Access group, while 23.7% belonged to the Watch group. There were no prescriptions of antibiotics from the Reserve group. The average number of antibiotics per prescription was 1.51 (SD ± 0.725). The percentage of antibiotic prescribing was 97.5%, with 96.20% by injection. All antibiotics prescribed were on the essential medicines list and prescribed by generic name. These results are concerning and highlight the urgency of strengthening antimicrobial optimization measures, as well as implementing the AWaRe framework in antibiotic prescribing as an essential strategy to combat AMR.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Padrões de Prática Médica / Antibacterianos Limite: Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Região como assunto: Africa Idioma: En Revista: Sci Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Padrões de Prática Médica / Antibacterianos Limite: Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Região como assunto: Africa Idioma: En Revista: Sci Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido