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A systematic review and meta-analysis of the prevalence of Parkinson's disease in lower to upper-middle-income countries.
Pereira, Gabriela Magalhães; Teixeira-Dos-Santos, Daniel; Soares, Nayron Medeiros; Marconi, Gabriel Alves; Friedrich, Deise Cristine; Saffie Awad, Paula; Santos-Lobato, Bruno Lopes; Brandão, Pedro Renato P; Noyce, Alastair J; Marras, Connie; Mata, Ignacio F; Rieder, Carlos Roberto de Mello; Schuh, Artur Francisco Schumacher.
Afiliação
  • Pereira GM; Programa de Pós-Graduação em Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
  • Teixeira-Dos-Santos D; Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
  • Soares NM; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.
  • Marconi GA; Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
  • Friedrich DC; Programa de Pós-Graduação em Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
  • Saffie Awad P; Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
  • Santos-Lobato BL; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.
  • Brandão PRP; Programa de Pós-Graduação em Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
  • Noyce AJ; Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
  • Marras C; Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
  • Mata IF; Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica de Porto Alegre, Porto Alegre, RS, Brazil.
  • Rieder CRM; Programa de Pós-Graduação em Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
  • Schuh AFS; Laboratório de Neuropatologia Experimental, Universidade Federal do Pará, Belém, PA, Brazil.
NPJ Parkinsons Dis ; 10(1): 181, 2024 Sep 30.
Article em En | MEDLINE | ID: mdl-39349513
ABSTRACT
Parkinson's disease (PD) is a common neurodegenerative disease that is a growing public health challenge. Estimates of the burden of PD have focused on data from high-income countries, with lower-income countries poorly described. We reviewed and examined the prevalence of PD reported by studies in low- to upper-middle-income countries. A systematic literature search was performed in the Medline/PubMed, Embase, LILACS, and Web of Science databases. Age group, sex, and geographic region were considered when analyzing the data. Of the 4327 assessed articles, 57 met the inclusion criteria for qualitative review, and 36 were included in the meta-analysis. Heterogeneity measures were high both as a whole and in each geographic region. Data analysis by geographic region showed that reported prevalence differed across regions, ranging from 49 per 100,000 (Sub-Saharan Africa) to 1081 per 100,000 (Latin America and the Caribbean). There was an increasing prevalence of PD with advancing age (per 100,000) 7 in 40-49 years, 158 in 50-59 years, 603 in 60-69 years, 1251 in 70-79 years, and 2181 in over the age of 80. The prevalence of PD in men and women was similar. There was a greater PD prevalence in populations with a higher 5-year GDP per capita and a higher life expectancy. Our findings suggest a higher prevalence of PD in lower and upper-middle-income countries than previously reported. Comparisons between regions are difficult, as the sociocultural differences and lack of methodological standardization hinder understanding key epidemiological data in varied populations.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: NPJ Parkinsons Dis Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: NPJ Parkinsons Dis Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos