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Heat stress affects milk yield, milk quality, and gene expression profiles in mammary cells of Girolando cows.
Mendonca, L C; Carvalho, W A; Campos, M M; Souza, G N; de Oliveira, S A; Meringhe, G K F; Negrao, J A.
Afiliação
  • Mendonca LC; São Paulo State University (UNESP), Faculty of Agricultural and Veterinary Sciences, Campus Jaboticabal; Brazilian Agricultural Research Corporation (Embrapa Dairy Cattle), Juiz de Fora, Minas Gerais, 36038-330, Brazil.
  • Carvalho WA; Brazilian Agricultural Research Corporation (Embrapa Dairy Cattle), Juiz de Fora, Minas Gerais, 36038-330, Brazil.
  • Campos MM; Brazilian Agricultural Research Corporation (Embrapa Dairy Cattle), Juiz de Fora, Minas Gerais, 36038-330, Brazil.
  • Souza GN; Brazilian Agricultural Research Corporation (Embrapa Dairy Cattle), Juiz de Fora, Minas Gerais, 36038-330, Brazil.
  • de Oliveira SA; Department of Basic Sciences, Faculty of Animal Science and Food Engineering (FZEA), University of São Paulo (USP), Pirassununga, SP, 13635-900 Brazil.
  • Meringhe GKF; Department of Basic Sciences, Faculty of Animal Science and Food Engineering (FZEA), University of São Paulo (USP), Pirassununga, SP, 13635-900 Brazil.
  • Negrao JA; Department of Basic Sciences, Faculty of Animal Science and Food Engineering (FZEA), University of São Paulo (USP), Pirassununga, SP, 13635-900 Brazil. Electronic address: jnegrao@usp.br.
J Dairy Sci ; 2024 Sep 27.
Article em En | MEDLINE | ID: mdl-39343218
ABSTRACT
Heat stress during lactation affects the physiological responses, hormonal release, health, and productivity of dairy cows. However, the adverse effects of heat stress on milk synthesis, immune response, and cellular apoptosis in mammary cells remains unknown in Bos indicus cows. This study aimed to understand the relationship between milk yield, milk quality, and the expression of genes related to milk synthesis, cell apoptosis, and immune response in mammary cells of Girolando cows. Twenty-four Girolando cows (3/4 Holstein and 1/4 Gir) were subjected to control (CT, with a temperature-humidity index ranging from 60 to 74, n = 12) or heat stress treatments (HS, with a temperature- humidity index ranging from 60 to 85, n = 12), from 111 to 120 d of lactation. Heat stress significantly increased the expression of heat shock proteins (HSPD1 and HSPD90AA1), insulin receptors (INSR), and prolactin receptors (PRLRsf) genes, and decreased the expression of glucocorticoid receptor (NR3C1) gene in mammary cells of the HS cows when compared with the CT cows. The HS cows exhibited significantly higher vaginal temperatures and cortisol release compared with the CT cows. Moreover, the HS cows had significantly lower dry matter intake and milk yield than CT cows. Although, HS cows showed higher percentage of lymphocytes in milk when compared with that from CT cows. There was no effect of heat stress on other leukocyte counts, somatic cell counts, bacterial counts in milk, or milk composition. Finally, this study demonstrated that Girolando cows are susceptible to heat stress, which decreases milk yield and affects the expression of genes linked to milk synthesis in the mammary cells.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Dairy Sci Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Dairy Sci Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos