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Prevalence and impact of vasomotor symptoms associated with menopause among women in Brazil: Subgroup analysis from an international cross-sectional survey.
Bonassi Machado, Rogério; Soler, Roberto; Freire, Marcos; Wender, Maria Celeste Osorio; Pompei, Luciano Melo.
Afiliação
  • Bonassi Machado R; Gynecology Department, Jundiai Medical School, R. Francisco Teles, 250, Vila Arens, Jundiai, São Paulo, SP 13202-550, Brazil.
  • Soler R; Medical Affairs, Astellas Pharma Brazil, Av. das Nações Unidas, 14171, Vila Gertrudes, São Paulo, SP 04730-090, Brazil. Electronic address: roberto.soler@astellas.com.
  • Freire M; Medical Affairs, Astellas Pharma Brazil, Av. das Nações Unidas, 14171, Vila Gertrudes, São Paulo, SP 04730-090, Brazil. Electronic address: marcos.freire@astellas.com.
  • Wender MCO; Obstetrics and Gynecology Department, Universidade Federal do Rio Grande do Sul, Farroupilha, Porto Alegre, RS 90010-150, Brazil; Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350 Bloco A, Av. Protásio Alves, 211, Bloco B e C, Santa Cecília, Porto Alegre, RS 90035-903, Brazil. Electron
  • Pompei LM; Disciplina de Ginecologia, Faculdade de Medicina do ABC, Av. Principe de Gales, 821, 2nd floor, Administrative Building, Santo Andre, SP 09060-650, Brazil. Electronic address: luciano.pompei@fmabc.net.
Maturitas ; 189: 108114, 2024 Nov.
Article em En | MEDLINE | ID: mdl-39317029
ABSTRACT

OBJECTIVE:

This study assessed the prevalence and impact of moderate and/or severe vasomotor symptoms and related treatment patterns in midlife women in Brazil. STUDY

DESIGN:

Brazilian women aged 40 to 65 years completed an online survey. The prevalence of moderate to severe vasomotor symptoms was assessed in postmenopausal women who completed a series of questionnaires to elicit responses regarding their treatment patterns and attitudes to treatments. MAIN OUTCOME

MEASURES:

Perimenopausal and postmenopausal women with moderate to severe vasomotor symptoms completed three standardized questionnaires (Menopause-Specific Quality of Life questionnaire, Work Productivity and Activity Impairment questionnaire, and the Patient-Reported Outcomes Measurement Information System Sleep Disturbances Short Form 8b) and answered open-ended questions.

RESULTS:

Of 1244 postmenopausal women who accessed the survey, 36.2 % had experienced moderate to severe vasomotor symptoms in the previous month. Moderate to severe vasomotor symptoms among 501 perimenopausal and postmenopausal women negatively affected overall quality of life (mean total score on the Menopause-Specific Quality of Life questionnaire was 3.6/8). On the Work Productivity and Activity Impairment questionnaire, women's scores for impairments in overall work and daily activities due to vasomotor symptoms were 50.3 % and 60.0 %, respectively. Overall mean (standard deviation) score on the Patient-Reported Outcomes Measurement Information System Sleep Disturbances Short Form 8b was 25.5 (5.8) on a scale of 8 to 40. Most women sought medical advice (65.5 %), but over half were not receiving treatment. Those who received treatment reported moderately favorable attitudes to hormone and nonhormone prescription medicines, but safety concerns remained.

CONCLUSION:

Brazilian women experienced a relatively high prevalence and burden of moderate to severe vasomotor symptoms.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Menopausa / Fogachos Limite: Adult / Aged / Female / Humans / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Maturitas Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Irlanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Menopausa / Fogachos Limite: Adult / Aged / Female / Humans / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Maturitas Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Irlanda