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Comparison of arterial stiffness index predictors in perimenopausal and postmenopausal women.
Gonçalves, Gleisy Kelly Neves; Ferreira, Thaize Prates; Cópio, Laís Alzamora; Castilho, César Teixeira; Rodrigues, Márcio Alexandre Hipólito; Rodrigues-Machado, Maria da Glória.
Afiliação
  • Gonçalves GKN; Post-Graduate Program in Health Sciences, Faculty of Medical Sciences of Minas Gerais (FCM-MG), Belo Horizonte, Brazil.
  • Ferreira TP; Medicine School, Faculty of Medical Sciences of Minas Gerais (FCM-MG), Belo Horizonte, Brazil.
  • Cópio LA; Medicine School, Faculty of Medical Sciences of Minas Gerais (FCM-MG), Belo Horizonte, Brazil.
  • Castilho CT; Physical Education School, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
  • Rodrigues MAH; Obstetrics and Gynecology Department School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
  • Rodrigues-Machado MDG; Post-Graduate Program in Health Sciences, Faculty of Medical Sciences of Minas Gerais (FCM-MG), Belo Horizonte, Brazil.
Women Health ; 64(9): 724-735, 2024 Oct.
Article em En | MEDLINE | ID: mdl-39302289
ABSTRACT
The present cross-sectional study aimed to compare climacteric symptoms and arterial stiffness indices between perimenopausal and postmenopausal women. The study sample comprised 70 healthy female participants, including 27 perimenopausal (49.8 ± 3.8 years) and 43 postmenopausal (55.7 ± 4 years) individuals. Validated methods were used to assess physical activity level, quality of life, climacteric symptoms, and anthropometric data. Arterial stiffness parameters were measured using Mobil-O-Graph. Pulse wave velocity (PWV) had a higher mean in the postmenopausal group than in the perimenopause group [8.04 m/s (SD 0.79) vs 7.01 m/s (SD 0.78), p < .001). PWV was strongly correlated with peripheral (r = 0.619) and central (r = 0.632) Systolic Blood Pressure (SBP) in postmenopausal group and an even stronger correlation was observed in perimenopausal group (r = 0.779 pSBP and 0.782 cSBP). BMI was a risk predictor in the perimenopausal group contributing positively to increase Pulse Pressure Amplification (PPA) (0.458, p < .05). In postmenopausal women, heart rate (HR) was a stronger predictor for central SBP, cardiac output, and total vascular resistance, whereas perimenopausal women HR influenced central diastolic blood pressure and PPA. Vascular changes initiating during perimenopause may contribute to the development of cardiovascular pathologies in the postmenopausal period. Further research with larger, representative samples is warranted to corroborate these findings.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Pressão Sanguínea / Pós-Menopausa / Perimenopausa / Rigidez Vascular / Análise de Onda de Pulso / Frequência Cardíaca Limite: Female / Humans / Middle aged Idioma: En Revista: Women Health Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Pressão Sanguínea / Pós-Menopausa / Perimenopausa / Rigidez Vascular / Análise de Onda de Pulso / Frequência Cardíaca Limite: Female / Humans / Middle aged Idioma: En Revista: Women Health Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos