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Effective treatment of collecting duct carcinoma in a recipient of a kidney transplant: A case report.
Nascimento de Assis, Tabata Carolina Faria; Rapatoni, Liane; Segato, Flavio Nogueira; Maciel Pontes, Barbhara Thais; Muglia, Valdair Francisco; Neto, Miguel Moyses; Almeida Romao, Elen.
Afiliação
  • Nascimento de Assis TCF; Division of Nephrology, Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048-900, Brazil.
  • Rapatoni L; Division of Clinical Oncology, Department of Medical Imaging, Haematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048-900, Brazil.
  • Segato FN; Division of Clinical Oncology, Department of Medical Imaging, Haematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048-900, Brazil.
  • Maciel Pontes BT; Division of Nephrology, Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048-900, Brazil.
  • Muglia VF; Division of Medical Imaging, Department of Medical Imaging, Haematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048-900, Brazil.
  • Neto MM; Division of Nephrology, Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048-900, Brazil.
  • Almeida Romao E; Division of Nephrology, Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo 14048-900, Brazil.
Oncol Lett ; 28(5): 528, 2024 Nov.
Article em En | MEDLINE | ID: mdl-39290954
ABSTRACT
Collecting duct carcinoma (CDC) is a rare disease associated with a high mortality rate. The present study describes the case of a recipient of a kidney transplant with metastatic allograft CDC whose treatment was successful. The patient underwent nephrectomy, and chemotherapy with gemcitabine and cisplatin, while undergoing haemodialysis treatment and remained in remission after 6 years of follow-up. There is a lack of information about the treatment and clinical management of CDC; however, the combination of gemcitabine and cisplatin remains as first-line therapy. The challenge of this case was integrating chemotherapy sessions with dialysis therapy to maintain the effectiveness, tolerability and safety of the oncological treatment. In the present case report, the success of chemotherapy with gemcitabine and cisplatin was demonstrated in a metastatic renal allograft CDC in a patient with end-stage renal disease, with few side effects and no recurrence of the disease 6 years after the end of treatment.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Oncol Lett Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Grécia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Oncol Lett Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Grécia