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Revealing the hidden threats: Genotoxic effects of microplastics on freshwater fish.
Menezes, Maiara; Teixeira de Mello, Franco; Ziegler, Lucia; Wanderley, Bruno; Gutiérrez, Juan Manuel; Dias, Juliana Deo.
Afiliação
  • Menezes M; Programa de Pós-graduação em Ecologia, Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil.
  • Teixeira de Mello F; Departamento de Ecología y Gestión Ambiental, Centro Universitario Regional del Este, Universidad de la República, Maldonado, Uruguay.
  • Ziegler L; Departamento de Ecología y Gestión Ambiental, Centro Universitario Regional del Este, Universidad de la República, Maldonado, Uruguay.
  • Wanderley B; Department of Oceanography and Limnology, Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN 59090-002, Brazil.
  • Gutiérrez JM; Departamento de Ecología y Gestión Ambiental, Centro Universitario Regional del Este, Universidad de la República, Maldonado, Uruguay.
  • Dias JD; Department of Oceanography and Limnology, Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN 59090-002, Brazil. Electronic address: juliana.dias@ufrn.br.
Aquat Toxicol ; 276: 107089, 2024 Sep 10.
Article em En | MEDLINE | ID: mdl-39276606
ABSTRACT
New evidence regarding the risks that microplastics (MP) ingestion pose to human and wildlife health are being revealed with progress made in ecotoxicological research. However, comprehensive and realistic approaches that evaluate multiple physiological responses simultaneously are still scarce despite their relevance to understand whole-organism effects. To address this information gap, we performed an experiment to assess the effects of MP on freshwater fish physiology from the molecular to the organismal level. Using a model species of global commercial importance (Cyprinus carpio) and MP type (recycling industry fragments), size (range between 125-1000 µm), and two concentrations of environmental relevance (0.75 and 8.25 µg/L). Experimental design included 5 blocks containing 3 treatment levels each one control, low, and high MP concentration, with 6 fish each aquarium (5 blocks x 3 treatments x 6 fish per aquarium = 90 fish). Our results suggest that, under the experimental conditions applied, MP exposure did not cause adverse effects at the morphological (variation in size of gut), metabolic (variation of standard metabolic rate), or ecological (growth performance) levels. Nonetheless, we observed an increased frequency of micronucleated cells with increasing MP concentration (df = 42, t-value = 3.68, p-value < 0.001), showing the potential genotoxicity of MP, which can clearly harm fish health in long-term. Thus, despite being a highly resistant species, exposure to MP may generate negative effects in juvenile C. carpio at cellular or subcellular levels. Our findings highlight that the manifestation of MP effects may vary over time, emphasizing the need for future studies to consider longer exposure durations in experimental designs.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Aquat Toxicol Assunto da revista: BIOLOGIA / TOXICOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Aquat Toxicol Assunto da revista: BIOLOGIA / TOXICOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda