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Asymmetric Nanobowl Confinement-Engineered "Plasmonic Storms" for Machine Learning-Assisted Ultrasensitive Immunochromatographic Assay of Pathogens.
Li, Yuechun; Cui, Zhaowen; Shi, Longhua; Bao, Qinyuan; Shu, Rui; Zhu, Wenxin; Zhang, Wentao; Ji, Yanwei; Shen, Yizhong; Cheng, Jie; Wang, Jianlong.
Afiliação
  • Li Y; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
  • Cui Z; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
  • Shi L; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
  • Bao Q; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
  • Shu R; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
  • Zhu W; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
  • Zhang W; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
  • Ji Y; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
  • Shen Y; School of Food & Biological Engineering, Anhui Province Key Laboratory of Agricultural Products Modern Processing, Hefei University of Technology, Hefei 230009, China.
  • Cheng J; Institute of Quality Standards and Testing Technologies for Agro-Products, Chinese Academy of Agricultural Sciences, No. 12 Zhongguancun South St., Haidian District, Beijing 100081, China.
  • Wang J; College of Food Science and Engineering, Northwest A&F University, 22 Xinong Road, Yangling, Shaanxi 712100, China.
Anal Chem ; 2024 Sep 09.
Article em En | MEDLINE | ID: mdl-39252431
ABSTRACT
Efficient field enhancement effects through plasmonic chemistry for ultrasensitive biosensing still face a great challenge. Herein, nanoconfinement engineering accumulation and synergistic effects are used to develop a "plasmonic storms" strategy with a high field enhancement effect, and gold nanoparticles (AuNPs) are used as active sites for a proof of concept because of their distinctive localized surface plasmon resonance and neighborly coupled electromagnetic field. Briefly, a large number of AuNPs are selectively and accurately stacked in the confined nanocavity of the bowl-like nanostructure through an in situ-synthesized strategy, which provides a space for strong coupling of electromagnetic fields between these adjacent AuNPs, forming "plasmonic storms" with an enhanced field that is 3 orders of magnitude higher than that of free AuNPs. The proposed nanoconfinement-engineered "plasmonic storms" are demonstrated by surface-enhanced Raman scattering (SERS) and photothermal experiments and theoretically visualized by finite element simulation. Finally, the proposed "plasmonic storms" are used for enhanced colorimetric/SERS/photothermal immunochromatographic assay to detect Salmonella typhimurium with the help of a machine learning algorithm, achieving a low limit of detection of 142 CFU mL-1, highlighting the potential of nanoconfinement in biosensing.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Anal Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Anal Chem Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos