Your browser doesn't support javascript.
loading
The relationship between brain structure volumes, depressive symptoms and body composition in obese/overweight and normal-/underweight women.
Lapinska, Lidia; Szum-Jakubowska, Aleksandra; Krentowska, Anna; Pawlak, Mikolaj; Hladunski, Marcin; Waszkiewicz, Napoleon; Karczewska-Kupczewska, Monika; Kaminski, Karol; Kowalska, Irina.
Afiliação
  • Lapinska L; Department of Internal Medicine and Metabolic Diseases, Medical University of Bialystok, M. Sklodowskiej-Curie 24a, 15-276, Bialystok, Poland. lidia.lapinska@umb.edu.pl.
  • Szum-Jakubowska A; Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.
  • Krentowska A; Department of Internal Medicine and Metabolic Diseases, Medical University of Bialystok, M. Sklodowskiej-Curie 24a, 15-276, Bialystok, Poland.
  • Pawlak M; Department of Neurology, Poznan University of Medical Sciences, Poznan, Poland.
  • Hladunski M; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Waszkiewicz N; Independent Laboratory of Molecular Imaging, Medical University of Bialystok, Bialystok, Poland.
  • Karczewska-Kupczewska M; Department of Psychiatry, Medical University of Bialystok, Bialystok, Poland.
  • Kaminski K; Department of Internal Medicine and Metabolic Diseases, Medical University of Bialystok, M. Sklodowskiej-Curie 24a, 15-276, Bialystok, Poland.
  • Kowalska I; Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.
Sci Rep ; 14(1): 21021, 2024 09 09.
Article em En | MEDLINE | ID: mdl-39251805
ABSTRACT
Depressive symptoms are highly prevalent and heterogeneous in women. Different brain structures might be associated with depressive symptoms and body composition in women with obesity/overweight and normal-/underweight, although the data is limited. The analysis included 265 women from Bialystok PLUS population study, untreated with antidepressive or antipsychotic medications. The subjects underwent brain magnetic resonance imaging and body composition analysis. Beck Depression Inventory (BDI) score was inversely associated with nucleus accumbens volume (ß = -0.217, p = 0.008) in women with BMI ≥ 25 kg/m2, but with insula volume (ß = -0.147, p = 0.027) in women with BMI < 25 kg/m2 after adjustment for age and estimated intracranial volume (eTIV). In women with BMI ≥ 25 kg/m2, nucleus accumbens volume was inversely associated with the percentage of visceral fat and BDI score (ß = -0.236, p = 0.012, ß = -0.192, p = 0.017) after adjustment for age and eTIV. In women with BMI < 25 kg/m2, insula volume was positively associated with total fat-free mass and negatively with the BDI score (ß = 0.142, p = 0.030, ß = -0.137, p = 0.037) after adjustment for age and eTIV. Depressive symptoms might be associated with nucleus accumbens volume in overweight/obese women, while in normal-/ underweight women-with alterations in insula volume.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Composição Corporal / Encéfalo / Imageamento por Ressonância Magnética / Depressão / Sobrepeso / Obesidade Limite: Adult / Female / Humans / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Polônia País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Composição Corporal / Encéfalo / Imageamento por Ressonância Magnética / Depressão / Sobrepeso / Obesidade Limite: Adult / Female / Humans / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Polônia País de publicação: Reino Unido