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Meta-Analysis of the Efficacy of Intense Pulsed Light and Pulsed-Dye Laser Therapy in the Management of Rosacea.
Zhai, Qianyu; Cheng, Shaohang; Liu, Runying; Xie, Jinying; Han, Xiao; Yu, Zhen.
Afiliação
  • Zhai Q; Department of Dermatology, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, China.
  • Cheng S; Department of Dermatology, Shenzhen People's Hospital, Shenzhen, Guangdong, China.
  • Liu R; Department of Dermatology, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, China.
  • Xie J; Department of Dermatology, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, China.
  • Han X; Department of Dermatology, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, China.
  • Yu Z; Department of Dermatology, Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong, China.
J Cosmet Dermatol ; 2024 Sep 06.
Article em En | MEDLINE | ID: mdl-39240125
ABSTRACT

OBJECTIVE:

The primary aim of this systematic review and meta-analysis was to synthesize and compare the clinical efficacy of intense pulsed light (IPL) and pulsed-dye laser (PDL) therapies for the management of rosacea.

METHODS:

The literatures were searched in the Web of Science, PubMed, Embase, and Cochrane Library databases to identify relevant studies investigating the use of IPL and PDL for the treatment of rosacea. Screening of the retrieved articles and data extraction were performed as per the pre-established inclusion and exclusion criteria. The primary outcome measures evaluated in this meta-analysis included clearance rates, erythema scores, and pain scores.

RESULTS:

The meta-analysis incorporated data from four studies involving a total of 141 participants. The meta-analysis did not reveal a statistically significant difference between IPL and PDL in the rate of achieving greater than 50% clearance (RR = -0.07, 95% CI -0.19, 0.05). However, the IPL group demonstrated a significantly higher rate of clearance exceeding 75% compared to the PDL group (RR = -0.13, 95% CI -0.23, -0.04). The change in erythema index, a key measure of rosacea severity, was similar between the two treatment modalities (SMD = -0.15, 95% CI -0.55, 0.26). Interestingly, the PDL group reported a notably lower VAS pain score than the IPL group (SMD = 1.54, 95% CI 0.08, 3.00).

CONCLUSION:

Either PDL or IPL appears to be effective modalities for the management of rosacea. IPL exhibits a slight advantage in achieving a higher rate of substantial (>75%) clearance, while PDL may be preferable for patients with lower tolerance for post-treatment discomfort. However, the existing literature directly comparing these two laser/light-based therapies is limited, warranting further well-designed, large-scale studies to establish the optimal treatment algorithm for this chronic inflammatory skin condition.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Cosmet Dermatol Assunto da revista: DERMATOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Cosmet Dermatol Assunto da revista: DERMATOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido