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Disorders of gut-brain interaction are common diagnoses among infants and toddlers in gastroenterology practices in Latin-America.
Velasco-Benítez, Carlos A; Alvarez-Baumgartner, Maura; Ortiz-Rivera, Claudia J; Velasco-Suárez, Daniela A; Zarzosa, Fátima A R; Ramírez, Mariana X E; Macías-Flores, Jorge A; Córdova, Roberto A Z; Águila, Ricardo A C; Castro, Milton D M; Suazo, Yunuen R; Balda, Amber N; Saps, Miguel.
Afiliação
  • Velasco-Benítez CA; Pediatrics Department, Universidad del Valle, Cali, Colombia.
  • Alvarez-Baumgartner M; Pediatrics Department, University of Miami, Miami, Florida, USA.
  • Ortiz-Rivera CJ; Pediatrics Department, Universidad del Valle, Cali, Colombia.
  • Velasco-Suárez DA; Grupo de Investigación Gastrohnup Univalle, Cali, Colombia.
  • Zarzosa FAR; Hospital Universitario de Puebla, BUAP, Puebla, México.
  • Ramírez MXE; Hospital General de Cancún "Dr. Jesús Kumate Rodríguez", Cancún, Chihuahua, Mexico.
  • Macías-Flores JA; Hospital Infantil de Especialidades, Chihuahua, Mexico.
  • Córdova RAZ; Clínica de Gastroenterología Pediátrica Dr. Roberto Zablah, San Salvador, El Salvador.
  • Águila RAC; Hospital del Niño, "Dr. José Renán Esquivel", Ciudad de Panamá, Panama.
  • Castro MDM; Centro de Gastroenterología, Endoscopia y Nutrición Pediátrica, Managua, Nicaragua.
  • Suazo YR; Unidad de Especialidades Médicas, Ciudad de México, Mexico.
  • Balda AN; Division of Pediatric Gastroenterology, Hepatology and Nutrition, University of Miami, Miami, Florida, USA.
  • Saps M; Division of Pediatric Gastroenterology, Hepatology and Nutrition, University of Miami, Miami, Florida, USA.
Article em En | MEDLINE | ID: mdl-39233517
ABSTRACT

OBJECTIVES:

To assess the relative frequency and associated factors of disorders of gut-brain interaction (DGBIs) in outpatient gastrointestinal (GI) clinics in young children of Latin America.

METHODS:

Cross-sectional study in 10 pediatric GI outpatient clinics (private and public) in five countries of Latin America (El Salvador, México, Colombia, Panamá, and Nicaragua). Parents of patients 1 month 4 years of age from outpatient clinics complete/d a diagnostic questionnaire for DGBIs per Rome IV criteria (QPGS-IV, Spanish version). We conducted descriptive analysis, two-sample t-tests and chi-square tests, univariate analyses, and logistic regression to evaluate risk factors.

RESULTS:

We collected data from 783 children. In total, 34.5% had a DGBI. Overall, functional constipation (FC) was the most common diagnosis (23.4%) in children of all ages (infants, 16.1%, 1-4-years-old, 32.7%). In infants, the second most common DGBI was regurgitation (6.6%) and in 1-4-years-old and cyclic vomiting syndrome (4.1%). The diagnosis of a DGBI was significantly associated with a family history of DGBIs (odds ratio [OR] 2.97, 95% confidence interval [CI] 1.61-5.57, p = 0.0001). Patients who identified as black (OR 2.25, 95% CI 1.28-3.92, p = 0.0021) or mixed race (OR 1.76, 95% CI 1.25-2.48, p = 0.0006) were also significantly associated with a higher likelihood of DGBIs.

CONCLUSIONS:

DGBIs are a common diagnosis in pediatric GI clinics of Latin America. Overall, FC was the most common DGBI.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Pediatr Gastroenterol Nutr Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Pediatr Gastroenterol Nutr Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Estados Unidos