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Clinical-Epidemiological Profile of COVID-19 Patients Admitted during Three Waves of the Pandemic in a Tertiary Care Center, in Belém, Pará, Amazon Region of Brazil.
Pereira, Ana Beatriz Nunes; Pereira, Fernando Sérgio Henriques; Araújo, Júlio Éden Davi Lopes; Brasil, Rangel Pereira; Oliveira, Angélica Menezes Bessa; Lima, Sandra Souza; Fonseca, Ricardo Roberto de Souza; Laurentino, Rogério Valois; Oliveira-Filho, Aldemir Branco; Machado, Luiz Fernando Almeida.
Afiliação
  • Pereira ABN; Biology of Infectious and Parasitic Agents Post-Graduate Program, Federal University of Pará, Belém 66075-110, PA, Brazil.
  • Pereira FSH; Virology Laboratory, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil.
  • Araújo JÉDL; Belém Health Department, Humberto Maradei Pereira Municipal and Emergency Hospital, Belém 66075-259, PA, Brazil.
  • Brasil RP; Belém Health Department, Humberto Maradei Pereira Municipal and Emergency Hospital, Belém 66075-259, PA, Brazil.
  • Oliveira AMB; Belém Health Department, Humberto Maradei Pereira Municipal and Emergency Hospital, Belém 66075-259, PA, Brazil.
  • Lima SS; Belém Health Department, Humberto Maradei Pereira Municipal and Emergency Hospital, Belém 66075-259, PA, Brazil.
  • Fonseca RRS; Virology Laboratory, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil.
  • Laurentino RV; Virology Laboratory, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil.
  • Oliveira-Filho AB; Virology Laboratory, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil.
  • Machado LFA; Study and Research Group on Vulnerable Populations, Institute for Coastal Studies, Federal University of Pará, Bragança 68600-000, PA, Brazil.
Viruses ; 16(8)2024 Jul 31.
Article em En | MEDLINE | ID: mdl-39205207
ABSTRACT

BACKGROUND:

Coronavirus disease 2019 (COVID-19) is a disease with a broad clinical spectrum, which may result in hospitalization in healthcare units, intensive care, and progression to death. This study aimed to describe and compare the clinical and epidemiological profile of COVID-19 during the three waves of the disease, in patients admitted to a public hospital in the city of Belém, Pará, in the Amazon region of Brazil.

METHODS:

This descriptive, observational, and cross-sectional study was population-based on individuals who were hospitalized with a diagnosis of COVID-19, confirmed by real-time reverse transcription-polymerase chain reaction (RT-PCR), and who were interviewed and monitored at the public hospital, from February 2020 to April 2022.

RESULTS:

The prevalence was male patients, older than 60 years. The most frequent symptoms were dyspnea, cough, and fever. Systemic arterial hypertension was the most prevalent comorbidity followed by diabetes mellitus. Less than 15% of patients were vaccinated. The nasal oxygen cannula was the most used oxygen therapy interface followed by the non-rebreathing reservoir mask. Invasive mechanical ventilation predominated and the median time of invasive mechanical ventilation ranged from 2 to 6 days among waves. As for the hospital outcome, transfers prevailed, followed by deaths and discharges.

CONCLUSION:

The presence of comorbidities, advanced age, and male sex were important factors in the severity and need for hospitalization of these patients, and the implementation of the vaccination policy was an essential factor in reducing the number of hospital admissions.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Centros de Atenção Terciária / SARS-CoV-2 / COVID-19 / Hospitalização Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Viruses Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Centros de Atenção Terciária / SARS-CoV-2 / COVID-19 / Hospitalização Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Viruses Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça