Molecular Epidemiology of Western Equine Encephalitis Virus, South America, 2023-2024.
Emerg Infect Dis
; 30(9): 1834-1840, 2024 Sep.
Article
em En
| MEDLINE
| ID: mdl-39173662
ABSTRACT
Western equine encephalitis virus (WEEV) is a mosquitoborne virus that reemerged in December 2023 in Argentina and Uruguay, causing a major outbreak. We investigated the outbreak using epidemiologic, entomological, and genomic analyses, focusing on WEEV circulation near the ArgentinaâUruguay border in Rio Grande do Sul state, Brazil. During November 2023âApril 2024, the outbreak in Argentina and Uruguay resulted in 217 human cases, 12 of which were fatal, and 2,548 equine cases. We determined cases on the basis of laboratory and clinical epidemiologic criteria. We characterized 3 fatal equine cases caused by a novel WEEV lineage identified through a nearly complete coding sequence analysis, which we propose as lineage C. Our findings highlight the importance of continued surveillance and equine vaccination to control future WEEV outbreaks in South America.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Filogenia
/
Surtos de Doenças
/
Epidemiologia Molecular
/
Vírus da Encefalite Equina do Oeste
Limite:
Adult
/
Animals
/
Female
/
Humans
/
Male
País/Região como assunto:
America do sul
/
Argentina
/
Uruguay
Idioma:
En
Revista:
Emerg Infect Dis
Assunto da revista:
DOENCAS TRANSMISSIVEIS
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
Estados Unidos