Your browser doesn't support javascript.
loading
Epidemiologic study of visceral leishmaniasis in Honduras, 1975-1983.
Am J Trop Med Hyg ; 34(6): 1069-75, 1985 Nov.
Article em En | MEDLINE | ID: mdl-3914845
Between 1975 and 1983, 53 patients with parasitologically proven visceral leishmaniasis (VL) and 16 patients with suspected VL were diagnosed in Honduras. The patients' ages ranged from 3 months to 10 years, but 95% were younger than 3 years old. Since 1978, when 16 patients were reported, the yearly incidence has declined, and in 1982 only 4 patients were reported. We located and interviewed the families of 57 of the 69 patients. At the onset of illness, all 57 patients lived in rural areas, and 55 lived in southern Honduras. All the patients who were discharged from the hospital alive were still living at the time of the interview. A case-control study, using age-matched neighbors as controls, showed that patients were significantly more likely to have lived in poorly constructed, wood-stick houses. We used an indirect immunofluorescence test to analyze blood samples for Leishmania antibodies from 218 family members of patients, 170 family members of controls, and 156 children living on the island of El Tigre, where 4 of the 5 most recently diagnosed patients lived. Although 15 specimens gave a positive reaction to L. donovani antigen, each gave a stronger reaction when tested against Trypanosoma cruzi antigen, suggesting that the reactions to L. donovani were false positives. A serosurvey of 279 dogs of cases and controls and from El Tigre showed that 24 had positive reactions to L. donovani antigen, but only 4 (1.4%) had higher titers to L. donovani than to T. cruzi.(ABSTRACT TRUNCATED AT 250 WORDS)
Assuntos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leishmaniose Visceral Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Animals / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: America central / Honduras Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 1985 Tipo de documento: Article País de publicação: Estados Unidos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leishmaniose Visceral Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Animals / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: America central / Honduras Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 1985 Tipo de documento: Article País de publicação: Estados Unidos