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Cosmetic Preservative Potential and Chemical Composition of Lafoensia replicata Pohl. Leaves.
Lima, Débora Machado de; Santos, Anna Lívia Oliveira; Melo, Matheus Reis Santos de; Tavares, Denise Crispim; Martins, Carlos Henrique Gomes; Sousa, Raquel Maria Ferreira.
Afiliação
  • Lima DM; Chemistry Instituto, Federal University of Uberlândia, Av. João Naves de Ávila 2121, Uberlândia 38400-902, MG, Brazil.
  • Santos ALO; Institute of Biomedical Sciences, Federal University of Uberlândia, Av. João Naves de Ávila 2121, Uberlândia 38400-902, MG, Brazil.
  • Melo MRS; University of Franca, Av. Dr. Armando Salles Oliveira, 201, Franca 14404-600, SP, Brazil.
  • Tavares DC; University of Franca, Av. Dr. Armando Salles Oliveira, 201, Franca 14404-600, SP, Brazil.
  • Martins CHG; Institute of Biomedical Sciences, Federal University of Uberlândia, Av. João Naves de Ávila 2121, Uberlândia 38400-902, MG, Brazil.
  • Sousa RMF; Chemistry Instituto, Federal University of Uberlândia, Av. João Naves de Ávila 2121, Uberlândia 38400-902, MG, Brazil.
Plants (Basel) ; 13(15)2024 Jul 23.
Article em En | MEDLINE | ID: mdl-39124129
ABSTRACT
The study evaluated the preservative potential of Lafoensia replicata Pohl. leaf extracts in cosmetics, highlighting their antioxidant, antimicrobial, and in vitro cytotoxic activities for ethanolic extract prepared by the maceration and tincture method. Total phenol content showed a higher phenol concentration in ethanolic extract and tinctures, and by LC-MS/MS-ESI-QTOF analysis, flavonoids, hydrolyzed tannins, and phenolic acids were identified. The ethanolic extract and tincture showed high antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans (MIC < 50 µg mL-1), high antioxidant activity (EC50 < 50 µg mL-1 in the DPPH method, and results > 450 µmol trolox equivalent in the ABTS and FRAP method), and low cytotoxicity in human keratinocytes (IC50 > 350 µg mL-1). The results suggest these extracts could be an alternative to synthetic preservatives in the cosmetic industry.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Plants (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Plants (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça