Your browser doesn't support javascript.
loading
Efficacy and threshold dose of intensive training targeting mobility for children with cerebral palsy: A systematic review and meta-analysis.
Sudati, Isabella Pessóta; Sakzewski, Leanne; Fioroni Ribeiro da Silva, Carolina; Jackman, Michelle; Haddon, Matthew; Pool, Dayna; Patel, Maharshi; Boyd, Roslyn N; de Campos, Ana Carolina.
Afiliação
  • Sudati IP; Physical Therapy Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
  • Sakzewski L; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
  • Fioroni Ribeiro da Silva C; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
  • Jackman M; The Healthy Strides Foundation, Perth, Western Australia, Australia.
  • Haddon M; Physical Therapy Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
  • Pool D; Australasian Cerebral Palsy Clinical Trials Network CRE, The University of Queensland, Brisbane, Australia.
  • Patel M; Cerebral Palsy Alliance Research Institute, University of Sydney, Sydney, New South Wales, Australia.
  • Boyd RN; Physiotherapy Department, Perth Children's Hospital, Perth, Western Australia, Australia.
  • de Campos AC; Queensland Cerebral Palsy and Rehabilitation Research Centre, Faculty of Medicine, Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Dev Med Child Neurol ; 2024 Aug 06.
Article em En | MEDLINE | ID: mdl-39108099
ABSTRACT

AIM:

To systematically review the evidence for intensive mobility training in cerebral palsy (CP) and to determine the minimum effective dose to improve mobility.

METHOD:

Randomized controlled trials (RCTs) or quasi-RCTs that included participants with CP, and which used intensive task-oriented training (TOT) mobility interventions and reported mobility outcomes, were included. Five databases were searched; two independent reviewers selected studies and extracted data. The Grading of Recommendations Assessment, Development, and Evaluation system and the Cochrane Risk of Bias 2 tool were used to rate the certainty of evidence at the outcomes level and to determine the risk of bias respectively. Meta-analyses were conducted with clinically homogeneous studies. Threshold dose was analysed through meta-regression.

RESULTS:

Forty-six RCTs with 1449 participants (mean age range 1 year 2 months to 16 years 4 months) were included. TOT had statistically and clinically significant effects on walking speed (p = 0.001), cadence (p = 0.02), gross motor function (p = 0.03), and functional mobility (p = 0.009) compared with control interventions. The threshold dose was undeterminable owing to the high heterogeneity of studies.

INTERPRETATION:

TOT may improve walking speed, walking endurance, and balance. Studies with homogeneous samples and outcomes are needed to support clinical recommendations for intensive mobility interventions.
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Dev Med Child Neurol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Dev Med Child Neurol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido