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Effect of the use of potentially inappropriate medications on the mortality of Brazilian older adults: SABE cohort study.
Ramos, Karina Alves; de Oliveira Duarte, Yeda Aparecida; Freitas, Renata Lara; Boing, Alexandra Crispim; Santos, Jair Lício Ferreira; Bof de Andrade, Fabíola.
Afiliação
  • Ramos KA; René Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715 - Barro Preto, Belo Horizonte, MG 30.190-002, Brazil.
  • de Oliveira Duarte YA; Nursing School, University of São Paulo, São Paulo, Brazil.
  • Freitas RL; René Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715 - Barro Preto, Belo Horizonte, MG 30.190-002, Brazil.
  • Boing AC; Federal University of Santa Catarina, Florianopolis, SC, Brazil.
  • Santos JLF; Ribeirão Preto School of Medicine, University of São Paulo, Riberião Preto, Brazil.
  • Bof de Andrade F; René Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ), Av. Augusto de Lima, 1715 - Barro Preto, Belo Horizonte, MG 30.190-002, Brazil. Electronic address: fabiola.bof@fiocruz.br.
Geriatr Nurs ; 59: 256-260, 2024.
Article em En | MEDLINE | ID: mdl-39089144
ABSTRACT

OBJECTIVE:

Investigate the association between potentially inappropriate medication (PIM) use and the risk of death among community-dwelling older Brazilian adults.

METHODS:

Participants from the Health, Well-Being, and Aging Cohort Study (SABE) in São Paulo, Brazil, between 2000 and 2016 were included. The dependent variable was all-cause mortality, measured as the time elapsed until death. The exposure of interest was the use of PIM according to the Beers Criteria 2019 version. All covariates, except for sex and education, were considered time-varying.

RESULTS:

PIM use was not associated with mortality after adjusting for covariates (HR = 0.99; 95 % CI 0.88-1.12). There was a significant interaction between PIM use and age (HR = 0.98; 95 % CI 0.96-0.99).

CONCLUSION:

The association between PIM use and the risk of death was moderated by age. Future studies should consider the impact of necessary medication omissions when assessing the mortality risk associated with PIM use.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lista de Medicamentos Potencialmente Inapropriados Limite: Aged / Aged80 / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Geriatr Nurs Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lista de Medicamentos Potencialmente Inapropriados Limite: Aged / Aged80 / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Geriatr Nurs Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos