Your browser doesn't support javascript.
loading
Early Life Stress Influences Oxidative Stress Enzyme Activities in Liver, Heart, Kidney, Suprarenal Glands, and Pancreas in Male and Female Rat Pups.
Fenton Navarro, Bertha; Casimiro Aguayo, Alexis Abraham; Torres Gómez, Yayr Luis; Cervantes Alfaro, Miguel; Torner, Luz.
Afiliação
  • Fenton Navarro B; Laboratorio de Glicobiología y Farmacognosia, Facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo. Av. Dr. Rafael Carrillo S/N, Esq. Dr. Salvador González Herrejón Bosque, Cuauhtémoc, Morelia 58020, Michoacán, Mexico.
  • Casimiro Aguayo AA; Laboratorio de Glicobiología y Farmacognosia, Facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo. Av. Dr. Rafael Carrillo S/N, Esq. Dr. Salvador González Herrejón Bosque, Cuauhtémoc, Morelia 58020, Michoacán, Mexico.
  • Torres Gómez YL; Laboratorio de Glicobiología y Farmacognosia, Facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo. Av. Dr. Rafael Carrillo S/N, Esq. Dr. Salvador González Herrejón Bosque, Cuauhtémoc, Morelia 58020, Michoacán, Mexico.
  • Cervantes Alfaro M; Laboratorio de Neurociencias, Facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo, Morelia 58000, Michoacán, Mexico.
  • Torner L; Laboratorio de Neuroendocrinología, Centro de Investigación Biomédica de Michoacán, Instituto Mexicano del Seguro Social; Cam. de La Arboleda # 300, La Huerta, Morelia 58341, Michoacán, Mexico.
Antioxidants (Basel) ; 13(7)2024 Jul 02.
Article em En | MEDLINE | ID: mdl-39061871
ABSTRACT
Early life stress (ELS) is a risk factor for the development of chronic diseases resulting from functional alterations of organs in the cardiorespiratory and renal systems. This work studied the changes in oxidative stress enzyme activities (EAs) of SOD, CAT, GPX, GR, GST, NOS, MDA, and FRAP in different organs (heart, liver, kidney, adrenal glands (AGs), and pancreas) of male and female Sprague-Dawley rat pups on postnatal day (PN) 15, immediately after basal and acute or chronic stress conditions were accomplished, as follows basal control (BC; undisturbed maternal pups care), stress control (SC; 3 h maternal separation on PN15), basal maternal separation (BMS; daily 3 h maternal separation on PN 1-14), and stress maternal separation (SMS; daily 3 h maternal separation on PN 1-14 and 3 h maternal separation on PN15). Acute or long-term stress resulted in overall oxidative stress, increase in EA, and reduced antioxidant capacity in these organs. Some different response patterns, due to precedent SMS, were observed in specific organs, especially in the AGs. Acute stress exposure increases the EA, but chronic stress generates a response in the antioxidant system in some of the organs studied and is damped in response to a further challenge.
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Antioxidants (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Antioxidants (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Suíça