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Does the use of intra-alveolar honey after lower third molar extraction reduce postoperative inflammatory complications? A systematic review and meta-analysis.
de Souza, Glaciele Maria; Teles, Ana Cláudia Oliveira; Neri, Anna Marina Teixeira Rodrigues; Santos, Karina Kendelhy; Milani, Lara Moreira Jalles; Galvão, Endi Lanza; Falci, Saulo Gabriel Moreira.
Afiliação
  • de Souza GM; Department of Dentistry, Faculty of Biological and Health Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Rua da Glória, 187, Centro, Diamantina, MG, 39100-000, Brazil. glaciele.souza@ufvjm.edu.br.
  • Teles ACO; Department of Dentistry, Faculty of Biological and Health Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Rua da Glória, 187, Centro, Diamantina, MG, 39100-000, Brazil.
  • Neri AMTR; Department of Dentistry, Faculty of Biological and Health Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Rua da Glória, 187, Centro, Diamantina, MG, 39100-000, Brazil.
  • Santos KK; Department of Dentistry, Faculty of Biological and Health Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Rua da Glória, 187, Centro, Diamantina, MG, 39100-000, Brazil.
  • Milani LMJ; Department of Dentistry, Faculty of Biological and Health Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Rua da Glória, 187, Centro, Diamantina, MG, 39100-000, Brazil.
  • Galvão EL; Department of Physical Therapy, School of Biological and Health Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Minas Gerais, Brazil.
  • Falci SGM; Department of Dentistry, Faculty of Biological and Health Sciences, Federal University of Jequitinhonha and Mucuri Valleys, Rua da Glória, 187, Centro, Diamantina, MG, 39100-000, Brazil.
Oral Maxillofac Surg ; 28(4): 1479-1489, 2024 Dec.
Article em En | MEDLINE | ID: mdl-39048888
ABSTRACT

BACKGROUND:

Protocols are currently being studied in preventing postoperative complications after exodontia.

PURPOSE:

This systematic review and meta-analysis aims to evaluate whether the application of intra-alveolar honey reduces inflammatory complications after the extraction of mandibular third molars (CRD 42.023.467.041).

METHODS:

Searches were carried out in six electronic databases. Clinical trials comparing intra-alveolar honey administration with non-intervention or placebo after mandibular third molar extraction were selected to assess their impact on postoperative inflammatory parameters. The Cochrane ROB 2 tool was used to assess the bias risk in included studies, Stata software to conduct a meta-analysis for quantitative synthesis, and the GRADE system to evaluate the certainty of the evidence.

RESULTS:

This systematic review included 5 studies with 330 participants, and two studies were included in the meta-analysis. The results of the meta-analysis demonstrated that postoperative pain on the second day [MD - 1.05; 95% CI - 2 to - 0.1] and fifth day [MD - 0.97; 95% CI - 1.97 to - 0.03] was lower in the honey group compared to the control group. Total analgesic consumption [MD - 4.77; 95% CI - 6.73 to - 2.81] was also lower in patients in the intervention group. The descriptive results indicated that honey appears to be beneficial in controlling edema, reducing trismus, and improving healing after extraction of third molars. Alveolar osteitis showed inconclusive results.

CONCLUSIONS:

The use of intra-alveolar honey after extraction of mandibular third molars seem to be associated with pain reduction. For the other outcomes, the results remain uncertain.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor Pós-Operatória / Complicações Pós-Operatórias / Extração Dentária / Mel / Dente Serotino Limite: Humans Idioma: En Revista: Oral Maxillofac Surg Assunto da revista: ODONTOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor Pós-Operatória / Complicações Pós-Operatórias / Extração Dentária / Mel / Dente Serotino Limite: Humans Idioma: En Revista: Oral Maxillofac Surg Assunto da revista: ODONTOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha