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Unjustified use of amber necklaces for teething symptoms alleviation: Succinic acid release underperforms compared with natural skin bacteria production.
de Azevedo, Marcelle Maciel Fernandes; de Araújo, Caroline Souza; Fernandes-Freitas, Liana Bastos; Soviero, Vera Mendes; Valente, Ana Paula; Kelly da Silva Fidalgo, Tatiana.
Afiliação
  • de Azevedo MMF; Department of Preventive and Community Dentistry, Dental School, Rio de Janeiro State University, Rio de Janeiro, Brazil.
  • de Araújo CS; Department of Preventive and Community Dentistry, Dental School, Rio de Janeiro State University, Rio de Janeiro, Brazil.
  • Fernandes-Freitas LB; Collaborator at National Centre of Nuclear Magnetic Resonance/CENABIO, Medical Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Soviero VM; Department of Preventive and Community Dentistry, Dental School, Rio de Janeiro State University, Rio de Janeiro, Brazil.
  • Valente AP; National Centre of Nuclear Magnetic Resonance/CENABIO, Medical Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Kelly da Silva Fidalgo T; Department of Preventive and Community Dentistry, Dental School, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Int J Paediatr Dent ; 2024 Jul 19.
Article em En | MEDLINE | ID: mdl-39031911
ABSTRACT

BACKGROUND:

There is limited evidence of succinic acid release from amber necklace that justifies its biological plausibility.

AIM:

This study aimed to evaluate the release of succinic acid from Baltic amber beads in the presence of Staphylococcus epidermidis.

DESIGN:

The Baltic amber beads from the necklace were stratified according to their weight (average 0.05 g ± 0.067). Subsequently, the beads (n = 8) were submerged in 0.9% buffered saline (Control) or brain-heart infusion culture medium in the presence of a commercial strain of S. epidermidis, a resident skin bacterium incubated at 37°C for 24 h or 7 days. The samples were centrifuged, and the supernatants were analyzed by 1H Nuclear Magnetic Resonance. Multivariate analyses were adopted using the sparse partial least squares discriminant analysis method (p < .05).

RESULTS:

The group incubated with saline solution showed small release of succinic acid only after 7 days. In the groups with S. epidermidis, the release of succinic acid was observed in the both presence and absence of amber beads, indicating that succinic acid is a product released by bacteria.

CONCLUSIONS:

It was found that amber beads do not exhibit the ability to release expressive succinic acid, especially in a short period of time, which does not justify their use in infants. The most production of succinic acid is tributed to S. epidermidis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Int J Paediatr Dent Assunto da revista: ODONTOLOGIA / PEDIATRIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Int J Paediatr Dent Assunto da revista: ODONTOLOGIA / PEDIATRIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido