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Estimation of standing height in spina bifida: model development and validation.
Bertapelli, Fabio; Leonardi-Figueiredo, Marisa Maia; Martins, Emanuela Juvenal; Baptista, Cyntia Rogean de Jesus Alves de; Mattiello-Sverzut, Ana Claudia.
Afiliação
  • Bertapelli F; Faculdade de Medicina de Ribeirão Preto, Departamento de Ciências da Saúde, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • Leonardi-Figueiredo MM; Faculdade de Medicina de Ribeirão Preto, Departamento de Ciências da Saúde, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • Martins EJ; Faculdade de Medicina de Ribeirão Preto, Departamento de Ciências da Saúde, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • Baptista CRJA; Faculdade de Medicina de Ribeirão Preto, Departamento de Ciências da Saúde, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • Mattiello-Sverzut AC; Faculdade de Medicina de Ribeirão Preto, Departamento de Ciências da Saúde, Universidade de São Paulo, Ribeirão Preto, SP, Brazil. Electronic address: acms@fmrp.usp.br.
J Pediatr (Rio J) ; 100(6): 646-652, 2024.
Article em En | MEDLINE | ID: mdl-39030938
ABSTRACT

OBJECTIVE:

Childhood standing height has been estimated from arm span-related (heightAS) models. The authors aimed to develop and cross-validate a heightAS model in individuals with spina bifida (SB) and examine the accuracy of existing heightAS models.

METHODS:

Participants were individuals with sacral and low-lumbar SB (n = 14) and non-SB (n = 83), 7-16 years old. Arm span, age, sex, and group (SB vs. non-SB) were candidate height predictors. Sequential regression and leave-one-out cross-validation approaches were used for the model development (M1) and cross-validation (M1-M5). Existing models were an SB-specific model from Polfuss et al. (M2) and non-SB specific models from Gauld et al. (M3), Mulu et al. (M4), and Zverev et al. (M5) studies.

RESULTS:

Arm span and group explained 95 % of the variance in height (R2 = 0.95; p < 0.001; SEE = 3.666 cm) and were included in the M1. Mean differences between actual and estimated height were 0.0 cm (M1), 0.4 cm (M2), and 0.5 cm (M5), all not significant (p > 0.05). However, Bland-Altman analysis revealed some variability in the predictability of the models across participants with limits of agreement ranging from 7.4 to 10.9 cm. Considerable errors were observed with M3 (mean diff -5.58 cm, 95 % CI -1.6, -20.2 cm), and M4 (mean diff 10.5 cm, 95 % CI -13.8, -27.3 cm).

CONCLUSIONS:

Models (M1, M2 and M5) may accurately estimate standing height in groups of children with SB. However, due to the wide limits of agreement, caution is recommended when applying these models for individual height estimations.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estatura / Disrafismo Espinal Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: J Pediatr (Rio J) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estatura / Disrafismo Espinal Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: J Pediatr (Rio J) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil