Your browser doesn't support javascript.
loading
Long-term complications and outcomes of therapeutic embolization of cerebral arteriovenous malformations: a systematic review.
Lúcio, Vivianne Beatriz Dos Santos; Queiroz, Vinício Rufino; Lins, Cícero José Pacheco; Baggio, Jussara Almeida de Oliveira; Souza, Carlos Dornels Freire de.
Afiliação
  • Lúcio VBDS; Undergraduate Student, Universidade Federal de Alagoas (UFAL), Arapiraca (AL), Brazil.
  • Queiroz VR; Undergraduate Student, Universidade Federal de Alagoas (UFAL), Arapiraca (AL), Brazil.
  • Lins CJP; Neurosurgery, Ebersh, Hospital Universitário Professor Alberto Antunes (UFAL), Maceió (AL), Brazil.
  • Baggio JAO; Assistant Professor, Medicine school, Universidade Federal de Alagoas (UFAL), Arapiraca (AL), Brazil.
  • Souza CDF; Assistant Professor, Collegiate of Medicine, Universidade Federal do Vale do São Francisco (UNIVASP), Petrolina (PE), Brazil.
Sao Paulo Med J ; 142(5): e2022591, 2024.
Article em En | MEDLINE | ID: mdl-39016379
ABSTRACT

BACKGROUND:

Embolization is a promising treatment strategy for cerebral arteriovenous malformations (AVMs). However, consensus regarding the main complications or long-term outcomes of embolization in AVMs remains lacking.

OBJECTIVE:

To characterize the most prevalent complications and long-term outcomes in patients with AVM undergoing therapeutic embolization. DESIGN AND

SETTING:

This systematic review was conducted at the Federal University of Alagoas, Arapiraca, Brazil.

METHODS:

This systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Data were obtained from MEDLINE, PubMed, LILACS, and SciELO databases, which included the epidemiological profile of the population, characteristics of the proposed therapy, complications (hemorrhagic events and neurological deficits), and long-term outcomes (modified Rankin scale pre- and post-treatment, AVM recanalization, complete obliteration, and deaths).

RESULTS:

Overall, the analysis included 34 articles (2,799 patients). Grade III Spetzler-Martin AVMs were observed in 34.2% of cases. Notably, 39.3% of patients underwent embolization combined with radiosurgery. The most frequently reported long-term complication was hemorrhage, which occurred in 8.7% of patients at a mean follow-up period of 58.6 months. Further, 6.3% of patients exhibited neurological deficits after an average of 34.7 months. Complete obliteration was achieved in 51.4% of the cases after a mean period of 36 months. Recanalization of AVMs was observed in 3.5% of patients. Long-term death occurred in 4.0% of patients.

CONCLUSION:

Embolization of AVMs is an increasingly safe strategy with low long-term complications and satisfactory outcomes, especially in patients who have undergone combination therapies. SYSTEMATIC REVIEW REGISTRATION https//www.crd.york.ac.uk/prospero/ Registration number CRD42020204867.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Malformações Arteriovenosas Intracranianas / Embolização Terapêutica Limite: Humans Idioma: En Revista: Sao Paulo Med J Assunto da revista: MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Malformações Arteriovenosas Intracranianas / Embolização Terapêutica Limite: Humans Idioma: En Revista: Sao Paulo Med J Assunto da revista: MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil