Your browser doesn't support javascript.
loading
Lactate and base excess (BE) as markers of hypoperfusion and mortality in traumatic hemorrhagic shock in patients undergoing Damage Control: a historical cohort.
Reese, Fernanda Baeumle; Hubert, Flavia Castanho; Cosentino, Mariana Bruinje; Oliveira, Mirella Cristine DE; Réa Neto, Álvaro; Bernardelli, Rafaella Stradiotto; Matias, Jorge Eduardo.
Afiliação
  • Reese FB; - Universidade Federal do Paraná, Programa de Mestrado - Curitiba - PR - Brasil.
  • Hubert FC; - Universidade Federal do Paraná, Complexo Hospital de Clínicas da Universidade Federal do Paraná - Curitiba - PR - Brasil.
  • Cosentino MB; - Hospital do Trabalhador, Hospital do Trabalhador - Curitiba - PR - Brasil.
  • Oliveira MC; - Pontifícia Universidade Católica do Paraná (PUC-PR), Centro de estudos e pesquisa em Terapia Intensiva (CEPETI) - Curitiba - PR - Brasil.
  • Réa Neto Á; - Universidade Federal do Paraná, Departamento de Clínica Médica - Curitiba - PR - Brasil.
  • Bernardelli RS; - Pontifícia Universidade Católica do Paraná (PUC-PR), Centro de estudos e pesquisa em Terapia Intensiva (CEPETI) - Curitiba - PR - Brasil.
  • Matias JE; - Universidade Federal do Paraná, Programa de Mestrado - Curitiba - PR - Brasil.
Rev Col Bras Cir ; 51: e20243699, 2024.
Article em En, Pt | MEDLINE | ID: mdl-38985036
ABSTRACT

INTRODUCTION:

hemorrhagic shock is a significant cause of trauma-related deaths in Brazil and worldwide. This study aims to compare BE and lactate values at ICU admission and twenty-four hours after in identifying tissue hypoperfusion and mortality.

METHODS:

examines a historical cohort of trauma patients over eitheen years old submittet to damage control resuscitation approch upon hospital admission and were then admitted to the ICU. We collected and analyzed ISS, mechanism and type of trauma, need for renal replacement therapy, massive transfusion. BE, lactate, pH, bicarbonate at ICU admission and twenty-four hours later, and mortality data. The patients were grouped based on their BE values (≥-6 and <-6mmol/L), which were previously identified in the literature as predictors of severity. They were subsequently redivided using the most accurate values found in this sample. In addition to performing multivariate binary logistic regression. The data were compared using several statistical tests due to diversity and according to the indication for each variable.

RESULTS:

there were significant changes in perfusion upon admission to the Intensive Care Unit. BE is a statistically significant value for predicting mortality, as determined by using values from previous literature and from this study.

CONCLUSION:

the results demonstrate the importance of monitoring BE levels in the prediction of ICU mortality. BE proves to be a valuable bedside marker with quick results and wide availability.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Choque Hemorrágico / Biomarcadores / Ácido Láctico Limite: Adult / Female / Humans / Male / Middle aged Idioma: En / Pt Revista: Rev Col Bras Cir Ano de publicação: 2024 Tipo de documento: Article País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Choque Hemorrágico / Biomarcadores / Ácido Láctico Limite: Adult / Female / Humans / Male / Middle aged Idioma: En / Pt Revista: Rev Col Bras Cir Ano de publicação: 2024 Tipo de documento: Article País de publicação: Brasil