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Clinical boundary conditions for propagation-based X-ray phase contrast imaging: from bio-sample models targeting to clinical applications.
Gobo, M S S; Balbin, D R; Hönnicke, M G; Poletti, M E.
Afiliação
  • Gobo MSS; Departamento de Física, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil.
  • Balbin DR; Departamento de Física, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil.
  • Hönnicke MG; Instituto Latino-Americano de Ciências da Vida e da Natureza, Universidade Federal da Integração Latino-Americana, Foz do Iguaçu, Brazil.
  • Poletti ME; Departamento de Física, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil.
J Xray Sci Technol ; 32(4): 1163-1175, 2024.
Article em En | MEDLINE | ID: mdl-38943421
ABSTRACT

BACKGROUND:

Typical propagation-based X-ray phase contrast imaging (PB-PCI) experiments using polyenergetic sources are tested in very ideal conditions low-energy spectrum (mainly characteristic X-rays), small thickness and homogeneous materials considered weakly absorbing objects, large object-to-detector distance, long exposure times and non-clinical detector.

OBJECTIVE:

Explore PB-PCI features using boundary conditions imposed by a low power polychromatic X-ray source (X-ray spectrum without characteristic X-rays), thick and heterogenous materials and a small area imaging detector with high low-detection radiation threshold, elements commonly found in a clinical scenario.

METHODS:

A PB-PCI setup implemented using a microfocus X-ray source and a dental imaging detector was characterized in terms of different spectra and geometric parameters on the acquired images. Test phantoms containing fibers and homogeneous materials with close attenuation characteristics and animal bone and mixed soft tissues (bio-sample models) were analyzed. Contrast to Noise Ratio (CNR), system spatial resolution and Kerma values were obtained for all images.

RESULTS:

Phase contrast images showed CNR up to 15% higher than conventional contact images. Moreover, it is better seen when large magnifications (>3) and object-to-detector distances (>13 cm) were used. The influence of the spectrum was not appreciable due to the low efficiency of the detector (thin scintillator screen) at high energies.

CONCLUSIONS:

Despite the clinical boundary condition used in this work, regarding the X-ray spectrum, thick samples, and detection system, it was possible to acquire phase contrast images of biological samples.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imagens de Fantasmas Limite: Animals / Humans Idioma: En Revista: J Xray Sci Technol Assunto da revista: RADIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imagens de Fantasmas Limite: Animals / Humans Idioma: En Revista: J Xray Sci Technol Assunto da revista: RADIOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda