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Analysis of the Spread and Evolution of COVID-19 Mutations in Ecuador Using Open Data.
Guevara, Cesar; Coronel, Dennys; Salazar, Byron; Salazar, Jorge; Arias-Flores, Hugo.
Afiliação
  • Guevara C; Centro de Mecatrónica y Sistemas Interactivos-MIST, Universidad Tecnológica Indoamérica, Quito 170301, Ecuador.
  • Coronel D; Centro de Mecatrónica y Sistemas Interactivos-MIST, Universidad Tecnológica Indoamérica, Quito 170301, Ecuador.
  • Salazar B; Neurosurgery Department, Hospital de las Fuerzas Armadas HE-1, Quito 170136, Ecuador.
  • Salazar J; Neurosurgery Department, Metropolitano Hospital, Quito 170521, Ecuador.
  • Arias-Flores H; Centro de Mecatrónica y Sistemas Interactivos-MIST, Universidad Tecnológica Indoamérica, Quito 170301, Ecuador.
Life (Basel) ; 14(6)2024 Jun 07.
Article em En | MEDLINE | ID: mdl-38929718
ABSTRACT
Currently, the analyses of and prediction using COVID-19-related data extracted from patient information repositories compiled by hospitals and health organizations are of paramount importance. These efforts significantly contribute to vaccine development and the formulation of contingency techniques, providing essential tools to prevent resurgence and to effectively manage the spread of the disease. In this context, the present research focuses on analyzing the biological information of the SARS-CoV-2 viral gene sequences and the clinical data of COVID-19-affected patients using publicly accessible data from Ecuador. This involves considering variables such as age, gender, and geographical location to understand the evolution of mutations and their distributions across Ecuadorian provinces. The Cross-Industry Standard Process for Data Mining (CRISP-DM) methodology is applied for data analysis. Various data preprocessing and statistical analysis techniques are employed, including Pearson correlation, the chi-square test, and analysis of variance (ANOVA). Statistical diagrams and charts are used to facilitate a better visualization of the results. The results illuminate the genetic diversity of the virus and its correlation with clinical variables, offering a comprehensive understanding of the dynamics of COVID-19 spread in Ecuador. Critical variables influencing population vulnerability are highlighted, and the findings underscore the significance of mutation monitoring and indicate a need for global expansion of the research area.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Ecuador Idioma: En Revista: Life (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Equador País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: America do sul / Ecuador Idioma: En Revista: Life (Basel) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Equador País de publicação: Suíça