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What Can the Gut Microbiota of Animals Teach Us about the Relationship between Nutrition and Burden of Lifestyle Diseases?
Mafra, Denise; Borges, Natália A; Baptista, Beatriz G; Martins, Layla F; Borland, Gillian; Shiels, Paul G; Stenvinkel, Peter.
Afiliação
  • Mafra D; Graduate Program in Medical Sciences and Graduate Program in Nutrition Sciences, Federal Fluminense University (UFF), Niterói 24020-141, Brazil.
  • Borges NA; Graduate Program in Biological Sciences-Physiology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 21941-909, Brazil.
  • Baptista BG; Graduate Program in Food, Nutrition, and Health, Institute of Nutrition, State University of Rio de Janeiro (UERJ), Rio de Janeiro 21941-909, Brazil.
  • Martins LF; Graduate Program in Medical Sciences and Graduate Program in Nutrition Sciences, Federal Fluminense University (UFF), Niterói 24020-141, Brazil.
  • Borland G; Department of Biochemistry, Institute of Chemistry, University of São Paulo (USP), São Paulo 05508-220, Brazil.
  • Shiels PG; School of Molecular Biosciences, University of Glasgow, Glasgow G12 8QQ, UK.
  • Stenvinkel P; School of Molecular Biosciences, University of Glasgow, Glasgow G12 8QQ, UK.
Nutrients ; 16(11)2024 Jun 06.
Article em En | MEDLINE | ID: mdl-38892721
ABSTRACT
The gut microbiota performs several crucial roles in a holobiont with its host, including immune regulation, nutrient absorption, synthesis, and defense against external pathogens, significantly influencing host physiology. Disruption of the gut microbiota has been linked to various chronic conditions, including cardiovascular, kidney, liver, respiratory, and intestinal diseases. Studying how animals adapt their gut microbiota across their life course at different life stages and under the dynamics of extreme environmental conditions can provide valuable insights from the natural world into how the microbiota modulates host biology, with a view to translating these into treatments or preventative measures for human diseases. By modulating the gut microbiota, opportunities to address many complications associated with chronic diseases appear. Such a biomimetic approach holds promise for exploring new strategies in healthcare and disease management.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microbioma Gastrointestinal Limite: Animals / Humans Idioma: En Revista: Nutrients Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microbioma Gastrointestinal Limite: Animals / Humans Idioma: En Revista: Nutrients Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça