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Imaging Transcriptomics of the Brain for Schizophrenia.
Gu, Yue-Wen; Fan, Jing-Wen; Zhào, Hóngyi; Zhao, Shu-Wan; Liu, Xiao-Fan; Yu, Renqiang; Ren, Lei; Wang, Xinjiang; Yin, Hong; Cui, Long-Biao.
Afiliação
  • Gu YW; Department of Clinical Psychology, Air Force Medical University, Xi'an, China.
  • Fan JW; Department of Radiology, Xijing Hospital, Air Force Medical University, Xi'an, China.
  • Zhào H; Department of Clinical Psychology, Air Force Medical University, Xi'an, China.
  • Zhao SW; Department of Radiology, Xijing Hospital, Air Force Medical University, Xi'an, China.
  • Liu XF; Department of Neurology, NO. 984 Hospital of PLA, Beijing, China.
  • Yu R; Department of Clinical Psychology, Air Force Medical University, Xi'an, China.
  • Ren L; Department of Radiology, Xijing Hospital, Air Force Medical University, Xi'an, China.
  • Wang X; Department of Clinical Psychology, Air Force Medical University, Xi'an, China.
  • Yin H; Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Cui LB; Department of Clinical Psychology, Air Force Medical University, Xi'an, China.
Alpha Psychiatry ; 25(1): 9-14, 2024 Jan.
Article em En | MEDLINE | ID: mdl-38799487
ABSTRACT
Schizophrenia is a severe mental disorder with a neurodevelopmental origin. Although schizophrenia results from changes in the brain, the underlying biological mechanisms are unknown. Transcriptomics studies quantitative expression changes or qualitative changes of all genes and isoforms, providing a more meaningful biological insight. Magnetic resonance imaging (MRI) techniques play roles in revealing brain structure and function. We give a narrative focused review on the current transcriptome combined with MRI studies related to schizophrenia and summarize the research methodology and content of these studies to identify the research commonalities as well as the implications for future research, in an attempt to provide new insights into the mechanism, clinical diagnosis, and treatments of schizophrenia.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Alpha Psychiatry Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Turquia
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Alpha Psychiatry Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Turquia