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Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection.
Miranda, Júlio Abreu; Cruz, Yasmin Ferreira da; Girão, Ícaro Chaves; Souza, Fabia Julliana Jorge de; Oliveira, Wógenes Nunes de; Alencar, Éverton do Nascimento; Amaral-Machado, Lucas; Egito, Eryvaldo Sócrates Tabosa do.
Afiliação
  • Miranda JA; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, Brazil.
  • Cruz YFD; Pharmacy Department, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, Brazil.
  • Girão ÍC; Pharmacy Department, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, Brazil.
  • Souza FJJ; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, Brazil.
  • Oliveira WN; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, Brazil.
  • Alencar ÉDN; Laboratory of Micro and Nanostructured Systems (LaSMiNano), College of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, Brazil.
  • Amaral-Machado L; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.
  • Egito ESTD; Graduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, Brazil.
Pharmaceutics ; 16(5)2024 May 15.
Article em En | MEDLINE | ID: mdl-38794323
ABSTRACT
Sunscreen products are essential for shielding the skin from ultraviolet (UV) radiation, a leading cause of skin cancer. While existing products serve this purpose, there is a growing need to enhance their efficacy while minimizing potential systemic absorption of UV filters and associated toxicological risks. Liposomal-based formulations have emerged as a promising approach to address these challenges and develop advanced photoprotective products. These vesicular systems offer versatility in carrying both hydrophilic and lipophilic UV filters, enabling the creation of broad-spectrum sunscreens. Moreover, their composition based on phospholipids, resembling that of the stratum corneum, facilitates adherence to the skin's surface layers, thereby improving photoprotective efficacy. The research discussed in this review underscores the significant advantages of liposomes in photoprotection, including their ability to limit the systemic absorption of UV filters, enhance formulation stability, and augment photoprotective effects. However, despite these benefits, there remains a notable gap between the potential of liposomal systems and their utilization in sunscreen development. Consequently, this review emphasizes the importance of leveraging liposomes and related vesicular systems as innovative tools for crafting novel and more efficient photoprotective formulations.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça