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Autolyzed yeast and sodium butyrate supplemented alone to diets promoted improvements in performance, intestinal health and nutrient transporter in weaned piglets.
Correia, Amanda Medeiros; Genova, Jansller Luiz; Kim, Sung Woo; Abranches, Fernanda Fialho; Rocha, Gabriel Cipriano.
Afiliação
  • Correia AM; Muscle Biology and Nutrigenomics Laboratory, Department of Animal Science, Universidade Federal de Viçosa, Minas Gerais, Brazil.
  • Genova JL; Muscle Biology and Nutrigenomics Laboratory, Department of Animal Science, Universidade Federal de Viçosa, Minas Gerais, Brazil.
  • Kim SW; Department of Animal Science, North Carolina State University, Raleigh, NC, 27695, USA.
  • Abranches FF; Muscle Biology and Nutrigenomics Laboratory, Department of Animal Science, Universidade Federal de Viçosa, Minas Gerais, Brazil.
  • Rocha GC; Muscle Biology and Nutrigenomics Laboratory, Department of Animal Science, Universidade Federal de Viçosa, Minas Gerais, Brazil. gcrocha@ufv.br.
Sci Rep ; 14(1): 11885, 2024 05 24.
Article em En | MEDLINE | ID: mdl-38789563
ABSTRACT
This study investigated the effects of supplemental nucleotides, autolyzed yeast (Saccharomyces cerevisiae), and sodium butyrate in diets for nursery pigs on growth performance, diarrhea incidence, blood profile, intestinal morphology, mRNA expression of nutrient transporters, inflammatory markers, antioxidant profile, and tight junction proteins in the small intestine. One hundred eighty 21-day-old pigs (5.17 ± 0.57 kg) were assigned in a randomized block design to 1 of 4 dietary treatments (1) CON control, basal diet, (2) NUC CON + nucleotides, (3) YSC CON + lysed yeast S. cerevisiae, (4) ASB CON + acidifier sodium butyrate. Pigs were fed for 24 days, phase 1 (21-32 days) and 2 (32-45 days). During phase 1, YSC and ASB improved average daily gain (ADG) and feed conversion (FC) compared with CON. At the overall period, ASB improved ADG and YSC improved FC compared with CON. The NUC diet did not affect growth performance. The ASB increased ileal villus height compared to CON. The YSC and ASB reduced the number of Peyer's patches in the ileum compared with CON. The YSC increased mRNA expression of nutrient transporters (SMCT2, MCT1, and PepT1), tight junction proteins (OCL and ZO-1), antioxidants (GPX), and IL1-ß in the jejunum compared with CON. The ASB increased mRNA expression of nutrient transporters (SGLT1 and MCT1), tight junction proteins (OCL and ZO-1), and antioxidants (GPX and SOD) compared with CON. In conclusion, autolyzed yeast and sodium butyrate promoted growth performance by improving the integrity of the intestinal barrier, the mRNA expression of nutrient transporters, and antioxidant enzymes in the jejunum of nursery pigs whereas supplementation of nucleotides did not show such effects.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Desmame / Suplementos Nutricionais / Ácido Butírico / Ração Animal Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Desmame / Suplementos Nutricionais / Ácido Butírico / Ração Animal Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido