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Pre-Gestational Obesity and Gestational Weight Gain as Predictors of Childhood Obesity.
Hernández-Barrera, Lucía; Trejo-Valdivia, Belem; Téllez-Rojo, Martha María; Baccarelli, Andrea; Wright, Robert; Cantoral, Alejandra; Barquera, Simón.
Afiliação
  • Hernández-Barrera L; Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
  • Trejo-Valdivia B; Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico. Electronic address: bvaldivia@insp.mx.
  • Téllez-Rojo MM; Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
  • Baccarelli A; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Wright R; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Cantoral A; Health Department, Universidad Iberoamericana, Mexico City, Mexico.
  • Barquera S; Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Arch Med Res ; 55(4): 103006, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38763021
ABSTRACT

OBJECTIVE:

To evaluate the associations of pre-gestational body mass index (BMI) and gestational weight gain (GWG) with the risks of overweight, obesity, and adiposity in the first seven years of life in the offspring of a cohort of pregnant women.

METHODS:

Analysis of 751 mothers and their children participating in the PROGRESS cohort. These women were recruited in Mexico City between 2007 and 2010. Pre-gestational BMI was classified as normal, overweight, and obesity according to the WHO. GWG was calculated as the difference between the last reported pre-pregnancy weight and the pre-gestational weight and categorized as inadequate, adequate, or excessive, according to US IOM recommendations. Children's anthropometry was evaluated at 4-5 and 6-7 years of age. Adiposity was classified into three groups normal (BMI z-score and waist circumference), overweight (BMI z-score>1), and overweight plus abdominal obesity (OW+AO). A generalized structural equation model (GSEM) was constructed to account for the temporal relationship between variables and to assess direct and indirect effects.

RESULTS:

A total of 49.3% of the women had excessive (13.8 ± 4.2 kg) and 19.8% inadequate (3.15 ± 3.4 kg) GWG. Women with pre-gestational overweight or obesity were more likely to have excessive GWG (OR 1.9 [95% CI 1.32, 2.74] and 3.50 [95% CI 1.83, 6.69], respectively). In the GSEM, excessive GWG was directly associated with OW+AO at 4-5 years. At 6-7 years, pre-gestational obesity was associated with OW+AO.

CONCLUSION:

Pre-gestational obesity and excessive GWG were independent predictors of childhood obesity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Massa Corporal / Obesidade Infantil / Ganho de Peso na Gestação Limite: Adult / Child / Child, preschool / Female / Humans / Male / Pregnancy País/Região como assunto: Mexico Idioma: En Revista: Arch Med Res Assunto da revista: MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Massa Corporal / Obesidade Infantil / Ganho de Peso na Gestação Limite: Adult / Child / Child, preschool / Female / Humans / Male / Pregnancy País/Região como assunto: Mexico Idioma: En Revista: Arch Med Res Assunto da revista: MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos