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Epidemiological profile of neuroendocrine tumors in adults in Brazil.
Brunelli Pujatti, Priscilla; Paim, Verônica; Gonçalves, Rinaldo; Vilhena, Bruno; Bergmann, Anke; Santos Thuler, Luiz Cláudio; Bulzico, Daniel.
Afiliação
  • Brunelli Pujatti P; Serviço de Medicina Nuclear, Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brasil.
  • Paim V; Serviço de Medicina Nuclear, Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brasil.
  • Gonçalves R; Seção de Cirurgia Abdominopélvica, Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brasil.
  • Vilhena B; Seção de Oncologia Clínica, Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brasil.
  • Bergmann A; Programa de Epidemiologia Clínica, Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brasil.
  • Santos Thuler LC; Programa de Epidemiologia Clínica, Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brasil.
  • Bulzico D; Serviço de Medicina Nuclear, Instituto Nacional de Câncer (INCA), Rio de Janeiro, RJ, Brasil, hcheinquer@gmail.com.
Arch Endocrinol Metab ; 68: e230013, 2024 May 06.
Article em En | MEDLINE | ID: mdl-38709149
ABSTRACT

Objective:

Neuroendocrine tumors (NETs) are a set of diseases that originate from neuroendocrine cells, which comprises a diffuse endocrine system present in various organs of the body. These tumors are more frequent in the gastrointestinal tract (70%) and the bronchopulmonary system (20%-30%). A NET incidence rate of 1-5 per 100,000 inhabitants has been estimated for several European countries and the USA employing 20 years of data. However, no comprehensive studies on this rare neoplasm are available in Brazil. In this context, the aim of this study was to characterize the epidemiological NET profile in the country. Materials and

methods:

This is a retrospective descriptive observational study based on data from Hospital Cancer Records available at the Brazilian National Cancer Institute and the São Paulo Oncocentro Foundation. Demographic, clinical and treatmentrelated variables were analyzed from selected cases employing descriptive statistics. Results and

Conclusion:

A total of 15,859 cases were identified, most occurring in males (53.4%) and in individuals under 65 years old (63.3%). Small cell carcinoma was the most frequent histological type (46.7%). Bronchopulmonary tumors were the most frequent NETs, followed by pancreatic tumors, with cases mostly concentrated in high complexity centers in the Brazilian Southeast and treated mainly with surgery and chemotherapy, with over half of the patients diagnosed in advanced stages of the disease.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tumores Neuroendócrinos Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Arch Endocrinol Metab Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tumores Neuroendócrinos Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Arch Endocrinol Metab Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil